2cw7: Difference between revisions

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{{Seed}}
[[Image:2cw7.png|left|200px]]


<!--
==Crystal structure of intein homing endonuclease II==
The line below this paragraph, containing "STRUCTURE_2cw7", creates the "Structure Box" on the page.
<StructureSection load='2cw7' size='340' side='right'caption='[[2cw7]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2cw7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermococcus_kodakarensis_KOD1 Thermococcus kodakarensis KOD1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CW7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CW7 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_2cw7| PDB=2cw7 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cw7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cw7 OCA], [https://pdbe.org/2cw7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cw7 RCSB], [https://www.ebi.ac.uk/pdbsum/2cw7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cw7 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DPOL_THEKO DPOL_THEKO] Intein encoded endonucleases are thought to mediate intein mobility by site-specific recombination initiated by endonuclease cleavage at the "homing site" in gene that lack the intein. PI-PkoI recognizes 5'-GATTTAGATCCCTGTACC-3' and PI-PkoII recognizes 5'-CAGCTACTACGGTTAC-3'.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cw/2cw7_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cw7 ConSurf].
<div style="clear:both"></div>


===Crystal structure of intein homing endonuclease II===
==See Also==
 
*[[Endonuclease 3D structures|Endonuclease 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2CW7 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Thermococcus_kodakarensis Thermococcus kodakarensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CW7 OCA].
[[Category: Large Structures]]
 
[[Category: Thermococcus kodakarensis KOD1]]
==Reference==
[[Category: Fujiwara S]]
<ref group="xtra">PMID:16493661</ref><references group="xtra"/>
[[Category: Hashimoto H]]
[[Category: Thermococcus kodakarensis]]
[[Category: Imanaka T]]
[[Category: Fujiwara, S.]]
[[Category: Inoue T]]
[[Category: Hashimoto, H.]]
[[Category: Kai Y]]
[[Category: Imanaka, T.]]
[[Category: Matsumura H]]
[[Category: Inoue, T.]]
[[Category: Nishioka M]]
[[Category: Kai, Y.]]
[[Category: Takagi M]]
[[Category: Matsumura, H.]]
[[Category: Takahashi H]]
[[Category: Nishioka, M.]]
[[Category: Takagi, M.]]
[[Category: Takahashi, H.]]
[[Category: Hydrolase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 01:55:15 2009''
Retrieved from "https://proteopedia.org/2cw7"