1jys: Difference between revisions

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{{Seed}}
[[Image:1jys.png|left|200px]]


<!--
==Crystal Structure of E. coli MTA/AdoHcy Nucleosidase==
The line below this paragraph, containing "STRUCTURE_1jys", creates the "Structure Box" on the page.
<StructureSection load='1jys' size='340' side='right'caption='[[1jys]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1jys]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JYS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JYS FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene></td></tr>
{{STRUCTURE_1jys|  PDB=1jys  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jys FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jys OCA], [https://pdbe.org/1jys PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jys RCSB], [https://www.ebi.ac.uk/pdbsum/1jys PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jys ProSAT]</span></td></tr>
 
</table>
===Crystal Structure of E. coli MTA/AdoHcy Nucleosidase===
== Function ==
 
[https://www.uniprot.org/uniprot/MTNN_ECOLI MTNN_ECOLI] Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Can also use 5'-isobutylthioadenosine, 5'-n-butylthioadenosine, S-adenosyl-D-homocysteine, decarboxylated adenosylhomocysteine, deaminated adenosylhomocysteine and S-2-aza-adenosylhomocysteine as substrates.[HAMAP-Rule:MF_01684]
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_11591349}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 11591349 is the PubMed ID number.
  <jmolCheckbox>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jy/1jys_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_11591349}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1JYS is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JYS OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jys ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
<ref group="xtra">PMID:11591349</ref><references group="xtra"/>
</StructureSection>
[[Category: Adenosylhomocysteine nucleosidase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Cornell, K A.]]
[[Category: Large Structures]]
[[Category: Howell, P L.]]
[[Category: Cornell KA]]
[[Category: Lee, J E.]]
[[Category: Howell PL]]
[[Category: Riscoe, M K.]]
[[Category: Lee JE]]
[[Category: Dimer]]
[[Category: Riscoe MK]]
[[Category: Mixed alpha/beta]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 02:27:30 2009''
Retrieved from "https://proteopedia.org/1jys"