3ccu: Difference between revisions

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{{Seed}}
[[Image:3ccu.png|left|200px]]


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==Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation G2482C==
The line below this paragraph, containing "STRUCTURE_3ccu", creates the "Structure Box" on the page.
<StructureSection load='3ccu' size='340' side='right'caption='[[3ccu]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3ccu]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Haloarcula_marismortui Haloarcula marismortui]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CCU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CCU FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1MA:6-HYDRO-1-METHYLADENOSINE-5-MONOPHOSPHATE'>1MA</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OMG:O2-METHYLGUANOSINE-5-MONOPHOSPHATE'>OMG</scene>, <scene name='pdbligand=OMU:O2-METHYLURIDINE+5-MONOPHOSPHATE'>OMU</scene>, <scene name='pdbligand=PSU:PSEUDOURIDINE-5-MONOPHOSPHATE'>PSU</scene>, <scene name='pdbligand=SR:STRONTIUM+ION'>SR</scene>, <scene name='pdbligand=UR3:3-METHYLURIDINE-5-MONOPHOSHATE'>UR3</scene></td></tr>
{{STRUCTURE_3ccu| PDB=3ccu |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ccu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ccu OCA], [https://pdbe.org/3ccu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ccu RCSB], [https://www.ebi.ac.uk/pdbsum/3ccu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ccu ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RL2_HALMA RL2_HALMA] One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome (By similarity).[HAMAP-Rule:MF_01320_A]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cc/3ccu_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ccu ConSurf].
<div style="clear:both"></div>


===Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation G2482C===
==See Also==
 
*[[Ribosome 3D structures|Ribosome 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_18455733}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 18455733 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_18455733}}
 
==About this Structure==
3CCU is a 31 chains structure of sequences from [http://en.wikipedia.org/wiki/Haloarcula_marismortui Haloarcula marismortui]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CCU OCA].
 
==Reference==
<ref group="xtra">PMID:18455733</ref><references group="xtra"/>
[[Category: Haloarcula marismortui]]
[[Category: Haloarcula marismortui]]
[[Category: Blaha, G.]]
[[Category: Large Structures]]
[[Category: Gurel, G.]]
[[Category: Blaha G]]
[[Category: 23s rrna]]
[[Category: Gurel G]]
[[Category: G2482c mutation]]
[[Category: Large ribosomal subunit]]
[[Category: Ribosome]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 02:36:55 2009''

Latest revision as of 09:34, 21 February 2024

Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation G2482C

3ccu, resolution 2.80Å

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