2apt: Difference between revisions

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New page: left|200px<br /><applet load="2apt" size="450" color="white" frame="true" align="right" spinBox="true" caption="2apt, resolution 2.000Å" /> '''Crystal Structure o...
 
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[[Image:2apt.gif|left|200px]]<br /><applet load="2apt" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2apt, resolution 2.000&Aring;" />
'''Crystal Structure of the G17E/S54N/K66E/Q72H/E80V/L81S/T87S/G96V variant of the murine T cell receptor V beta 8.2 domain'''<br />


==About this Structure==
==Crystal Structure of the G17E/S54N/K66E/Q72H/E80V/L81S/T87S/G96V variant of the murine T cell receptor V beta 8.2 domain==
2APT is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with MLA as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2APT OCA].  
<StructureSection load='2apt' size='340' side='right'caption='[[2apt]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2apt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2APT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2APT FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2apt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2apt OCA], [https://pdbe.org/2apt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2apt RCSB], [https://www.ebi.ac.uk/pdbsum/2apt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2apt ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A2NAI0_RAT A2NAI0_RAT]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ap/2apt_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2apt ConSurf].
<div style="clear:both"></div>


==Reference==
==See Also==
The nitty-gritty of protein interactions., Schreiber G, Structure. 2005 Dec;13(12):1737-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16338399 16338399]
*[[T-cell receptor 3D structures|T-cell receptor 3D structures]]
[[Category: Protein complex]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Cho, S.]]
[[Category: Cho S]]
[[Category: Guan, R.]]
[[Category: Guan R]]
[[Category: Kerzic, M.C.]]
[[Category: Kerzic MC]]
[[Category: Kieke, M.C.]]
[[Category: Kieke MC]]
[[Category: Kranz, D.M.]]
[[Category: Kranz DM]]
[[Category: Mariuzza, R.A.]]
[[Category: Mariuzza RA]]
[[Category: Sundberg, E.J.]]
[[Category: Sundberg EJ]]
[[Category: Swaminathan, C.P.]]
[[Category: Swaminathan CP]]
[[Category: Yang, J.]]
[[Category: Yang J]]
[[Category: MLA]]
[[Category: the murine t cell receptor v beta 8.2 domain]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 08:16:47 2007''

Latest revision as of 11:17, 22 May 2024

Crystal Structure of the G17E/S54N/K66E/Q72H/E80V/L81S/T87S/G96V variant of the murine T cell receptor V beta 8.2 domain

2apt, resolution 2.00Å

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