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New page: left|200px<br /><applet load="2aqr" size="450" color="white" frame="true" align="right" spinBox="true" caption="2aqr, resolution 1.75Å" /> '''CU/ZN superoxide dis...
 
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[[Image:2aqr.jpg|left|200px]]<br /><applet load="2aqr" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2aqr, resolution 1.75&Aring;" />
'''CU/ZN superoxide dismutase from neisseria meningitidis K91Q mutant'''<br />


==About this Structure==
==CU/ZN superoxide dismutase from neisseria meningitidis K91Q mutant==
2AQR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Neisseria_meningitidis Neisseria meningitidis] with CU1, CU and ZN as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2AQR OCA].  
<StructureSection load='2aqr' size='340' side='right'caption='[[2aqr]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2aqr]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_meningitidis Neisseria meningitidis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AQR FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=CU1:COPPER+(I)+ION'>CU1</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2aqr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aqr OCA], [https://pdbe.org/2aqr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2aqr RCSB], [https://www.ebi.ac.uk/pdbsum/2aqr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2aqr ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SODC_NEIMB SODC_NEIMB] Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aq/2aqr_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2aqr ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Superoxide dismutase 3D structures|Superoxide dismutase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Neisseria meningitidis]]
[[Category: Neisseria meningitidis]]
[[Category: Single protein]]
[[Category: Bruns CK]]
[[Category: Superoxide dismutase]]
[[Category: Cabelli DE]]
[[Category: Bruns, C.K.]]
[[Category: Cao Z]]
[[Category: Cabelli, D.E.]]
[[Category: DiDonato M]]
[[Category: Cao, Z.]]
[[Category: Getzoff ED]]
[[Category: DiDonato, M.]]
[[Category: Kassmann CJ]]
[[Category: Getzoff, E.D.]]
[[Category: Kroll JS]]
[[Category: Kassmann, C.J.]]
[[Category: Tabatabai LB]]
[[Category: Kroll, J.S.]]
[[Category: Tabatabai, L.B.]]
[[Category: CU]]
[[Category: CU1]]
[[Category: ZN]]
[[Category: cu/zn superoxide dismutase]]
[[Category: electrostatic guidance]]
[[Category: neisseria meningitidis]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 08:18:28 2007''
Retrieved from "https://proteopedia.org/2aqr"