2gzf: Difference between revisions

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{{Seed}}
[[Image:2gzf.png|left|200px]]


<!--
==Crystal structure of the E9 DNase domain with a mutant immunity protein IM9 (Y54F)==
The line below this paragraph, containing "STRUCTURE_2gzf", creates the "Structure Box" on the page.
<StructureSection load='2gzf' size='340' side='right'caption='[[2gzf]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2gzf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GZF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GZF FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_2gzf| PDB=2gzf |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gzf OCA], [https://pdbe.org/2gzf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gzf RCSB], [https://www.ebi.ac.uk/pdbsum/2gzf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gzf ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/IMM9_ECOLX IMM9_ECOLX] This protein is able to protect a cell, which harbors the plasmid ColE9 encoding colicin E9, against colicin E9, it binds specifically to the DNase-type colicin and inhibits its bactericidal activity.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gz/2gzf_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gzf ConSurf].
<div style="clear:both"></div>


===Crystal structure of the E9 DNase domain with a mutant immunity protein IM9 (Y54F)===
==See Also==
 
*[[Colicin 3D structures|Colicin 3D structures]]
 
*[[Colicin immunity protein 3D structures|Colicin immunity protein 3D structures]]
==About this Structure==
__TOC__
2GZF is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GZF OCA].
</StructureSection>
 
[[Category: Escherichia coli K-12]]
==Reference==
[[Category: Large Structures]]
<ref group="xtra">PMID:10074943</ref><references group="xtra"/>
[[Category: Hemmings AM]]
[[Category: Deoxyribonuclease I]]
[[Category: Kleanthous C]]
[[Category: Escherichia coli]]
[[Category: Kolade OO]]
[[Category: Hemmings, A M.]]
[[Category: Kuhlmann UC]]
[[Category: Kleanthous, C.]]
[[Category: Santi PS]]
[[Category: Kolade, O O.]]
[[Category: Kuhlmann, U C.]]
[[Category: Santi, P S.]]
[[Category: 4-helix bundle]]
[[Category: Dnase domain]]
[[Category: Hnh-motif]]
[[Category: Protein-protein complex]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 06:51:52 2009''

Latest revision as of 09:49, 30 August 2023

Crystal structure of the E9 DNase domain with a mutant immunity protein IM9 (Y54F)

2gzf, resolution 1.75Å

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