2agh: Difference between revisions

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{{Seed}}
[[Image:2agh.png|left|200px]]


<!--
==Structural basis for cooperative transcription factor binding to the CBP coactivator==
The line below this paragraph, containing "STRUCTURE_2agh", creates the "Structure Box" on the page.
<StructureSection load='2agh' size='340' side='right'caption='[[2agh]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2agh]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AGH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AGH FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2agh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2agh OCA], [https://pdbe.org/2agh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2agh RCSB], [https://www.ebi.ac.uk/pdbsum/2agh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2agh ProSAT]</span></td></tr>
{{STRUCTURE_2agh| PDB=2agh |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/MYB_MOUSE MYB_MOUSE] Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ag/2agh_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2agh ConSurf].
<div style="clear:both"></div>


===Structural basis for cooperative transcription factor binding to the CBP coactivator===
==See Also==
 
*[[CREB-binding protein 3D structures|CREB-binding protein 3D structures]]
 
*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
<!--  
__TOC__
The line below this paragraph, {{ABSTRACT_PUBMED_16253272}}, adds the Publication Abstract to the page
</StructureSection>
(as it appears on PubMed at http://www.pubmed.gov), where 16253272 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_16253272}}
 
==About this Structure==
2AGH is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AGH OCA].
 
==Reference==
<ref group="xtra">PMID:16253272</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Dyson, H J.]]
[[Category: De Guzman RN]]
[[Category: Goto, N K.]]
[[Category: Dyson HJ]]
[[Category: Guzman, R N.De.]]
[[Category: Goto NK]]
[[Category: Wright, P E.]]
[[Category: Wright PE]]
[[Category: Transcription]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 06:57:54 2009''
Retrieved from "https://proteopedia.org/2agh"