2b3w: Difference between revisions
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New page: left|200px<br /><applet load="2b3w" size="450" color="white" frame="true" align="right" spinBox="true" caption="2b3w" /> '''NMR structure of the E.coli protein YbiA, No... |
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== | ==NMR structure of the E.coli protein YbiA, Northeast Structural Genomics target ET24.== | ||
<StructureSection load='2b3w' size='340' side='right'caption='[[2b3w]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2b3w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B3W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B3W FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b3w OCA], [https://pdbe.org/2b3w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b3w RCSB], [https://www.ebi.ac.uk/pdbsum/2b3w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b3w ProSAT], [https://www.topsan.org/Proteins/NESGC/2b3w TOPSAN]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/RIBX_ECOLI RIBX_ECOLI] Catalyzes the hydrolysis of the N-glycosidic bond in the first two intermediates of riboflavin biosynthesis, which are highly reactive metabolites, yielding relatively innocuous products. Thus, can divert a surplus of harmful intermediates into relatively harmless products and pre-empt the damage these intermediates would otherwise do. Helps maintain flavin levels. May act on other substrates in vivo. Has no activity against GTP, nucleoside monophosphates or ADP-ribose (PubMed:25431972). Is Required for swarming motility (PubMed:17122336).<ref>PMID:17122336</ref> <ref>PMID:25431972</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b3/2b3w_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b3w ConSurf]. | |||
<div style="clear:both"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Acton | [[Category: Acton TB]] | ||
[[Category: Cort | [[Category: Cort JR]] | ||
[[Category: Kennedy | [[Category: Kennedy MA]] | ||
[[Category: Montelione | [[Category: Montelione GT]] | ||
[[Category: Ramelot TA]] | |||
[[Category: Ramelot | [[Category: Shih LY]] | ||
[[Category: Shih | [[Category: Xiao R]] | ||
[[Category: Xiao | |||
Latest revision as of 09:23, 22 May 2024
NMR structure of the E.coli protein YbiA, Northeast Structural Genomics target ET24.
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