1tj6: Difference between revisions
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==Crystal structure of the Xenopus tropicalis Spred1 EVH-1 domain== | |||
<StructureSection load='1tj6' size='340' side='right'caption='[[1tj6]], [[Resolution|resolution]] 1.65Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1tj6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Xenopus_tropicalis Xenopus tropicalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TJ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TJ6 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tj6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tj6 OCA], [https://pdbe.org/1tj6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tj6 RCSB], [https://www.ebi.ac.uk/pdbsum/1tj6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tj6 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SPRE1_XENTR SPRE1_XENTR] Tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase (By similarity). | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
== | Check<jmol> | ||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tj/1tj6_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tj6 ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Xenopus tropicalis]] | [[Category: Xenopus tropicalis]] | ||
[[Category: Amaya | [[Category: Amaya E]] | ||
[[Category: Blundell | [[Category: Blundell TL]] | ||
[[Category: Harmer | [[Category: Harmer NJ]] | ||
[[Category: Sivak | [[Category: Sivak J]] | ||
Latest revision as of 06:30, 23 August 2023
Crystal structure of the Xenopus tropicalis Spred1 EVH-1 domain
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