1mxi: Difference between revisions
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< | ==Structure of YibK from Haemophilus influenzae (HI0766): a Methyltransferase with a Cofactor Bound at a Site Formed by a Knot== | ||
<StructureSection load='1mxi' size='340' side='right'caption='[[1mxi]], [[Resolution|resolution]] 1.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1mxi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MXI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MXI FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mxi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mxi OCA], [https://pdbe.org/1mxi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mxi RCSB], [https://www.ebi.ac.uk/pdbsum/1mxi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mxi ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TRML_HAEIN TRML_HAEIN] Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.[HAMAP-Rule:MF_01885] | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mx/1mxi_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mxi ConSurf]. | |||
<div style="clear:both"></div> | |||
== | ==See Also== | ||
*[[TRNA methyltransferase 3D structures|TRNA methyltransferase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
< | |||
[[Category: Haemophilus influenzae]] | [[Category: Haemophilus influenzae]] | ||
[[Category: Bonander | [[Category: Large Structures]] | ||
[[Category: Eisenstein | [[Category: Bonander N]] | ||
[[Category: Herzberg | [[Category: Eisenstein E]] | ||
[[Category: Howard | [[Category: Herzberg O]] | ||
[[Category: Lim | [[Category: Howard A]] | ||
[[Category: Lim K]] | |||
[[Category: Tempczyk | [[Category: Tempczyk A]] | ||
[[Category: Toedt | [[Category: Toedt J]] | ||
[[Category: Zhang | [[Category: Zhang H]] | ||
Latest revision as of 07:49, 14 February 2024
Structure of YibK from Haemophilus influenzae (HI0766): a Methyltransferase with a Cofactor Bound at a Site Formed by a Knot
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