2nrc: Difference between revisions

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{{Seed}}
[[Image:2nrc.png|left|200px]]


<!--
==C28A Mutant of Succinyl-CoA:3-Ketoacid CoA Transferase from Pig Heart==
The line below this paragraph, containing "STRUCTURE_2nrc", creates the "Structure Box" on the page.
<StructureSection load='2nrc' size='340' side='right'caption='[[2nrc]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2nrc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NRC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NRC FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nrc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nrc OCA], [https://pdbe.org/2nrc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nrc RCSB], [https://www.ebi.ac.uk/pdbsum/2nrc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nrc ProSAT]</span></td></tr>
{{STRUCTURE_2nrc|  PDB=2nrc  |  SCENE=  }}
</table>
 
== Function ==
===C28A Mutant of Succinyl-CoA:3-Ketoacid CoA Transferase from Pig Heart===
[https://www.uniprot.org/uniprot/SCOT1_PIG SCOT1_PIG] Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
<!--
Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_17718512}}, adds the Publication Abstract to the page
  <jmolCheckbox>
(as it appears on PubMed at http://www.pubmed.gov), where 17718512 is the PubMed ID number.
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nr/2nrc_consurf.spt"</scriptWhenChecked>
-->
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_17718512}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2nrc ConSurf].
2NRC is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NRC OCA].  
<div style="clear:both"></div>
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:17718512</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: 3-oxoacid CoA-transferase]]
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
[[Category: Fraser, M E.]]
[[Category: Fraser ME]]
[[Category: Tammam, S D.]]
[[Category: Tammam SD]]
[[Category: Alpha/beta protein]]
[[Category: Transferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 11:30:24 2009''
Retrieved from "https://proteopedia.org/2nrc"