1a2q: Difference between revisions

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{{Seed}}
[[Image:1a2q.png|left|200px]]


<!--
==SUBTILISIN BPN' MUTANT 7186==
The line below this paragraph, containing "STRUCTURE_1a2q", creates the "Structure Box" on the page.
<StructureSection load='1a2q' size='340' side='right'caption='[[1a2q]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1a2q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_amyloliquefaciens Bacillus amyloliquefaciens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A2Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A2Q FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACN:ACETONE'>ACN</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MIS:MONOISOPROPYLPHOSPHORYLSERINE'>MIS</scene></td></tr>
{{STRUCTURE_1a2q| PDB=1a2q |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a2q OCA], [https://pdbe.org/1a2q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a2q RCSB], [https://www.ebi.ac.uk/pdbsum/1a2q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a2q ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SUBT_BACAM SUBT_BACAM] Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides. Has a high substrate specificity to fibrin.<ref>PMID:12524032</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a2/1a2q_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1a2q ConSurf].
<div style="clear:both"></div>


===SUBTILISIN BPN' MUTANT 7186===
==See Also==
 
*[[Subtilisin 3D structures|Subtilisin 3D structures]]
 
== References ==
<!--
<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_2684274}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 2684274 is the PubMed ID number.
</StructureSection>
-->
{{ABSTRACT_PUBMED_2684274}}
 
==About this Structure==
1A2Q is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_amyloliquefaciens Bacillus amyloliquefaciens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A2Q OCA].
 
==Reference==
<ref group="xtra">PMID:2684274</ref><references group="xtra"/>
[[Category: Bacillus amyloliquefaciens]]
[[Category: Bacillus amyloliquefaciens]]
[[Category: Subtilisin]]
[[Category: Large Structures]]
[[Category: Gilliland, G L.]]
[[Category: Gilliland GL]]
[[Category: Howard, A J.]]
[[Category: Howard AJ]]
[[Category: Whitlow, M.]]
[[Category: Whitlow M]]
[[Category: Hydrolase]]
[[Category: Serine protease]]
[[Category: Sporulation]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:14:47 2009''

Latest revision as of 15:20, 13 March 2024

SUBTILISIN BPN' MUTANT 7186

1a2q, resolution 1.80Å

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