3wrp: Difference between revisions

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{{Seed}}
[[Image:3wrp.png|left|200px]]


<!--
==FLEXIBILITY OF THE DNA-BINDING DOMAINS OF TRP REPRESSOR==
The line below this paragraph, containing "STRUCTURE_3wrp", creates the "Structure Box" on the page.
<StructureSection load='3wrp' size='340' side='right'caption='[[3wrp]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3wrp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WRP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WRP FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wrp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wrp OCA], [https://pdbe.org/3wrp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wrp RCSB], [https://www.ebi.ac.uk/pdbsum/3wrp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wrp ProSAT]</span></td></tr>
{{STRUCTURE_3wrp|  PDB=3wrp  |  SCENE=  }}
</table>
 
== Function ==
===FLEXIBILITY OF THE DNA-BINDING DOMAINS OF TRP REPRESSOR===
[https://www.uniprot.org/uniprot/TRPR_ECOLI TRPR_ECOLI] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
<!--
Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_3375234}}, adds the Publication Abstract to the page
  <jmolCheckbox>
(as it appears on PubMed at http://www.pubmed.gov), where 3375234 is the PubMed ID number.
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wr/3wrp_consurf.spt"</scriptWhenChecked>
-->
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_3375234}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3wrp ConSurf].
3WRP is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WRP OCA].  
<div style="clear:both"></div>
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:3375234</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Sigler, P B.]]
[[Category: Large Structures]]
[[Category: Zhang, R G.]]
[[Category: Sigler PB]]
[[Category: Dna binding regulatory protein]]
[[Category: Zhang R-G]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:51:16 2009''
Retrieved from "https://proteopedia.org/3wrp"