2dej: Difference between revisions

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New page: left|200px<br /><applet load="2dej" size="450" color="white" frame="true" align="right" spinBox="true" caption="2dej, resolution 1.50Å" /> '''Crystal Structure of...
 
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[[Image:2dej.jpg|left|200px]]<br /><applet load="2dej" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2dej, resolution 1.50&Aring;" />
'''Crystal Structure of galaktokinase from Pyrococcus horikoshii with AMP-PN and galactose'''<br />


==About this Structure==
==Crystal Structure of galaktokinase from Pyrococcus horikoshii with AMP-PN and galactose==
2DEJ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii] with GLA and APW as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Galactokinase Galactokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.6 2.7.1.6] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2DEJ OCA].  
<StructureSection load='2dej' size='340' side='right'caption='[[2dej]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
[[Category: Galactokinase]]
== Structural highlights ==
<table><tr><td colspan='2'>[[2dej]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DEJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DEJ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=APW:{5-O-[(R)-{[(S)-AMINO(HYDROXY-KAPPAO)PHOSPHORYL]OXY}(HYDROXY-KAPPAO)PHOSPHORYL]ADENOSINATO(2-)}MAGNESIUM'>APW</scene>, <scene name='pdbligand=GLA:ALPHA+D-GALACTOSE'>GLA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dej FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dej OCA], [https://pdbe.org/2dej PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dej RCSB], [https://www.ebi.ac.uk/pdbsum/2dej PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dej ProSAT], [https://www.topsan.org/Proteins/RSGI/2dej TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GAL1_PYRHO GAL1_PYRHO] Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).<ref>PMID:16511293</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/de/2dej_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dej ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Galactokinase|Galactokinase]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pyrococcus horikoshii]]
[[Category: Pyrococcus horikoshii]]
[[Category: Single protein]]
[[Category: Inagaki E]]
[[Category: Inagaki, E.]]
[[Category: Sakamoto K]]
[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
[[Category: Shinkai A]]
[[Category: Sakamoto, K.]]
[[Category: Yokoyama S]]
[[Category: Shinkai, A.]]
[[Category: Yokoyama, S.]]
[[Category: APW]]
[[Category: GLA]]
[[Category: adp analogue]]
[[Category: galactokinase]]
[[Category: galactose]]
[[Category: national project on protein structural and functional analyses]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomics]]
 
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