2dld: Difference between revisions

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New page: left|200px<br /><applet load="2dld" size="450" color="white" frame="true" align="right" spinBox="true" caption="2dld, resolution 2.7Å" /> '''D-LACTATE DEHYDROGENA...
 
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[[Image:2dld.gif|left|200px]]<br /><applet load="2dld" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2dld, resolution 2.7&Aring;" />
'''D-LACTATE DEHYDROGENASE COMPLEXED WITH NADH AND OXAMATE'''<br />


==About this Structure==
==D-LACTATE DEHYDROGENASE COMPLEXED WITH NADH AND OXAMATE==
2DLD is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Lactobacillus_helveticus Lactobacillus helveticus] with NAD and OXM as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/D-lactate_dehydrogenase D-lactate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.28 1.1.1.28] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2DLD OCA].  
<StructureSection load='2dld' size='340' side='right'caption='[[2dld]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
[[Category: D-lactate dehydrogenase]]
== Structural highlights ==
<table><tr><td colspan='2'>[[2dld]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lactobacillus_helveticus Lactobacillus helveticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DLD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DLD FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene>, <scene name='pdbligand=OXM:OXAMIC+ACID'>OXM</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dld FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dld OCA], [https://pdbe.org/2dld PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dld RCSB], [https://www.ebi.ac.uk/pdbsum/2dld PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dld ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LDHD_LACHE LDHD_LACHE]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dl/2dld_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dld ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Lactate dehydrogenase 3D structures|Lactate dehydrogenase 3D structures]]
__TOC__
</StructureSection>
[[Category: Lactobacillus helveticus]]
[[Category: Lactobacillus helveticus]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Dunn, C.R.]]
[[Category: Dunn CR]]
[[Category: Holbrook, J.J.]]
[[Category: Holbrook JJ]]
[[Category: NAD]]
[[Category: OXM]]
[[Category: oxidoreductase (choh(d)-nad+(a))]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 09:39:19 2007''

Latest revision as of 09:44, 25 December 2024

D-LACTATE DEHYDROGENASE COMPLEXED WITH NADH AND OXAMATE

2dld, resolution 2.70Å

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