2gle: Difference between revisions

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{{Seed}}
[[Image:2gle.png|left|200px]]


<!--
==Solution structure of neurabin SAM domain==
The line below this paragraph, containing "STRUCTURE_2gle", creates the "Structure Box" on the page.
<StructureSection load='2gle' size='340' side='right'caption='[[2gle]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2gle]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GLE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GLE FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gle FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gle OCA], [https://pdbe.org/2gle PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gle RCSB], [https://www.ebi.ac.uk/pdbsum/2gle PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gle ProSAT]</span></td></tr>
{{STRUCTURE_2gle|  PDB=2gle  |  SCENE=  }}
</table>
 
== Function ==
===Solution structure of neurabin SAM domain===
[https://www.uniprot.org/uniprot/NEB1_RAT NEB1_RAT] Binds to actin filaments (F-actin) and shows cross-linking activity. Binds along the sides of the F-actin. May be involved in neurite formation. Inhibits protein phosphatase 1-alpha activity. May play an important role in linking the actin cytoskeleton to the plasma membrane at the synaptic junction.
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
==About this Structure==
Check<jmol>
2GLE is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GLE OCA].  
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gl/2gle_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gle ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Hudak, J.]]
[[Category: Hudak J]]
[[Category: Ju, T.]]
[[Category: Ju T]]
[[Category: Peti, W.]]
[[Category: Peti W]]
[[Category: Protein protein interaction]]
[[Category: Sam domain]]
[[Category: Scaffold]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 13:49:14 2009''
Retrieved from "https://proteopedia.org/2gle"