2dn8: Difference between revisions

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New page: left|200px<br /><applet load="2dn8" size="450" color="white" frame="true" align="right" spinBox="true" caption="2dn8" /> '''Solution Structure of RSGI RUH-053, an Apo-B...
 
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[[Image:2dn8.jpg|left|200px]]<br /><applet load="2dn8" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2dn8" />
'''Solution Structure of RSGI RUH-053, an Apo-Biotin Carboxy Carrier Protein from Human Transcarboxylase'''<br />


==About this Structure==
==Solution Structure of RSGI RUH-053, an Apo-Biotin Carboxy Carrier Protein from Human Transcarboxylase==
2DN8 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Active as [http://en.wikipedia.org/wiki/Acetyl-CoA_carboxylase Acetyl-CoA carboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.4.1.2 6.4.1.2] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2DN8 OCA].  
<StructureSection load='2dn8' size='340' side='right'caption='[[2dn8]]' scene=''>
[[Category: Acetyl-CoA carboxylase]]
== Structural highlights ==
<table><tr><td colspan='2'>[[2dn8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DN8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DN8 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dn8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dn8 OCA], [https://pdbe.org/2dn8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dn8 RCSB], [https://www.ebi.ac.uk/pdbsum/2dn8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dn8 ProSAT], [https://www.topsan.org/Proteins/RSGI/2dn8 TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ACACB_HUMAN ACACB_HUMAN] ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dn/2dn8_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dn8 ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Acetyl-CoA carboxylase 3D structures|Acetyl-CoA carboxylase 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Hayashi, F.]]
[[Category: Hayashi F]]
[[Category: Hirota, H.]]
[[Category: Hirota H]]
[[Category: Momen, A.Z.M.Ruhul.]]
[[Category: Ruhul Momen AZM]]
[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: acetyl coa carboxylase]]
[[Category: biotin required enzyme]]
[[Category: national project on protein structural and functional analyses]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomics]]
[[Category: transcarboxylase]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 09:40:52 2007''

Latest revision as of 18:44, 29 May 2024

Solution Structure of RSGI RUH-053, an Apo-Biotin Carboxy Carrier Protein from Human Transcarboxylase

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