2dnv: Difference between revisions

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New page: left|200px<br /><applet load="2dnv" size="450" color="white" frame="true" align="right" spinBox="true" caption="2dnv" /> '''Solution Structure of RSGI RUH-055, a Chromo...
 
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[[Image:2dnv.jpg|left|200px]]<br /><applet load="2dnv" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2dnv" />
'''Solution Structure of RSGI RUH-055, a Chromo Domain from Mus musculus cDNA'''<br />


==About this Structure==
==Solution Structure of RSGI RUH-055, a Chromo Domain from Mus musculus cDNA==
2DNV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2DNV OCA].  
<StructureSection load='2dnv' size='340' side='right'caption='[[2dnv]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2dnv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DNV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DNV FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dnv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dnv OCA], [https://pdbe.org/2dnv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dnv RCSB], [https://www.ebi.ac.uk/pdbsum/2dnv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dnv ProSAT], [https://www.topsan.org/Proteins/RSGI/2dnv TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CBX8_MOUSE CBX8_MOUSE] Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dn/2dnv_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dnv ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Single protein]]
[[Category: Hirota H]]
[[Category: Hirota, H.]]
[[Category: Kigawa T]]
[[Category: Kigawa, T.]]
[[Category: Ruhul Momen AZM]]
[[Category: Momen, A.Z.M.Ruhul.]]
[[Category: Tomizawa T]]
[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
[[Category: Yokoyama S]]
[[Category: Tomizawa, T.]]
[[Category: Yokoyama, S.]]
[[Category: choromatin organization modifier]]
[[Category: chromo domain]]
[[Category: histone h3 tail]]
[[Category: national project on protein structural and functional analyses]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomics]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 09:41:35 2007''
Retrieved from "https://proteopedia.org/2dnv"