2ehh: Difference between revisions

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New page: left|200px<br /><applet load="2ehh" size="450" color="white" frame="true" align="right" spinBox="true" caption="2ehh, resolution 1.90Å" /> '''Crystal structure of...
 
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[[Image:2ehh.jpg|left|200px]]<br /><applet load="2ehh" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2ehh, resolution 1.90&Aring;" />
'''Crystal structure of dihydrodipicolinate synthase from aquifex aeolicus'''<br />


==About this Structure==
==Crystal structure of dihydrodipicolinate synthase from aquifex aeolicus==
2EHH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus] with PO4 as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Dihydrodipicolinate_synthase Dihydrodipicolinate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.52 4.2.1.52] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2EHH OCA].  
<StructureSection load='2ehh' size='340' side='right'caption='[[2ehh]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2ehh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EHH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EHH FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ehh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ehh OCA], [https://pdbe.org/2ehh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ehh RCSB], [https://www.ebi.ac.uk/pdbsum/2ehh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ehh ProSAT], [https://www.topsan.org/Proteins/RSGI/2ehh TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DAPA_AQUAE DAPA_AQUAE] Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA) (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eh/2ehh_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ehh ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Dihydrodipicolinate synthase|Dihydrodipicolinate synthase]]
__TOC__
</StructureSection>
[[Category: Aquifex aeolicus]]
[[Category: Aquifex aeolicus]]
[[Category: Dihydrodipicolinate synthase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Karthe P]]
[[Category: Karthe, P.]]
[[Category: Kumarevel TS]]
[[Category: Kumarevel, T.S.]]
[[Category: Kuramitsu S]]
[[Category: Kuramitsu, S.]]
[[Category: Yokoyama S]]
[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
[[Category: Yokoyama, S.]]
[[Category: PO4]]
[[Category: aquifex aeolicus]]
[[Category: dihydrodipicolinate synthase]]
[[Category: national project on protein structural and functional analyses]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomics]]
 
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Retrieved from "https://proteopedia.org/2ehh"