2etj: Difference between revisions

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New page: left|200px<br /><applet load="2etj" size="450" color="white" frame="true" align="right" spinBox="true" caption="2etj, resolution 1.740Å" /> '''Crystal structure o...
 
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[[Image:2etj.gif|left|200px]]<br /><applet load="2etj" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2etj, resolution 1.740&Aring;" />
'''Crystal structure of Ribonuclease HII (EC 3.1.26.4) (RNase HII) (tm0915) from THERMOTOGA MARITIMA at 1.74 A resolution'''<br />


==About this Structure==
==Crystal structure of Ribonuclease HII (EC 3.1.26.4) (RNase HII) (tm0915) from THERMOTOGA MARITIMA at 1.74 A resolution==
2ETJ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima] with MG, CL and EDO as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Ribonuclease_H Ribonuclease H], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.4 3.1.26.4] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2ETJ OCA].  
<StructureSection load='2etj' size='340' side='right'caption='[[2etj]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
[[Category: Ribonuclease H]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[2etj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ETJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ETJ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.74&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2etj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2etj OCA], [https://pdbe.org/2etj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2etj RCSB], [https://www.ebi.ac.uk/pdbsum/2etj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2etj ProSAT], [https://www.topsan.org/Proteins/JCSG/2etj TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RNH2_THEMA RNH2_THEMA] Endonuclease that specifically degrades the RNA of RNA-DNA hybrids (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/et/2etj_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2etj ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
[[Category: JCSG, Joint.Center.for.Structural.Genomics.]]
[[Category: CL]]
[[Category: EDO]]
[[Category: MG]]
[[Category: jcsg]]
[[Category: joint center for structural genomics]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: ribonuclease hii (ec 3.1.26.4) (rnase hii)]]
[[Category: structural genomics]]
[[Category: tm0915]]
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 10:08:13 2007''