2p5s: Difference between revisions

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{{Seed}}
[[Image:2p5s.png|left|200px]]


<!--
==RAB domain of human RASEF in complex with GDP==
The line below this paragraph, containing "STRUCTURE_2p5s", creates the "Structure Box" on the page.
<StructureSection load='2p5s' size='340' side='right'caption='[[2p5s]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2p5s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P5S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P5S FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
{{STRUCTURE_2p5s|  PDB=2p5s  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p5s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p5s OCA], [https://pdbe.org/2p5s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p5s RCSB], [https://www.ebi.ac.uk/pdbsum/2p5s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p5s ProSAT]</span></td></tr>
 
</table>
===RAB domain of human RASEF in complex with GDP===
== Function ==
 
[https://www.uniprot.org/uniprot/RASEF_HUMAN RASEF_HUMAN] Binds predominantly GDP, and also GTP.<ref>PMID:17448446</ref>
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
2P5S is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P5S OCA].  
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p5/2p5s_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p5s ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H.]]
[[Category: Large Structures]]
[[Category: Bochkarev, A.]]
[[Category: Arrowsmith CH]]
[[Category: Edwards, A M.]]
[[Category: Bochkarev A]]
[[Category: Landry, R.]]
[[Category: Edwards AM]]
[[Category: Park, H.]]
[[Category: Landry R]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Park H]]
[[Category: Shen, Y.]]
[[Category: Shen Y]]
[[Category: Sundstrom, M.]]
[[Category: Sundstrom M]]
[[Category: Tempel, W.]]
[[Category: Tempel W]]
[[Category: Wang, J.]]
[[Category: Wang J]]
[[Category: Weigelt, J.]]
[[Category: Weigelt J]]
[[Category: Zhu, H.]]
[[Category: Zhu H]]
[[Category: G-protein]]
[[Category: Gdp]]
[[Category: Rab]]
[[Category: Sgc]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 16:37:32 2009''
Retrieved from "https://proteopedia.org/2p5s"