1v5b: Difference between revisions

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{{Seed}}
[[Image:1v5b.png|left|200px]]


<!--
==The Structure Of The Mutant, S225A and E251L, Of 3-Isopropylmalate Dehydrogenase From Bacillus Coagulans==
The line below this paragraph, containing "STRUCTURE_1v5b", creates the "Structure Box" on the page.
<StructureSection load='1v5b' size='340' side='right'caption='[[1v5b]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1v5b]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Weizmannia_coagulans Weizmannia coagulans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V5B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V5B FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.95&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_1v5b| PDB=1v5b |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v5b OCA], [https://pdbe.org/1v5b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v5b RCSB], [https://www.ebi.ac.uk/pdbsum/1v5b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v5b ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LEU3_WEICA LEU3_WEICA] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v5/1v5b_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v5b ConSurf].
<div style="clear:both"></div>


===The Structure Of The Mutant, S225A and E251L, Of 3-Isopropylmalate Dehydrogenase From Bacillus Coagulans===
==See Also==
 
*[[Isopropylmalate dehydrogenase|Isopropylmalate dehydrogenase]]
 
__TOC__
==About this Structure==
</StructureSection>
1V5B is a 8 chains structure of sequences from [http://en.wikipedia.org/wiki/Bacillus_coagulans Bacillus coagulans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V5B OCA].
[[Category: Large Structures]]
[[Category: 3-isopropylmalate dehydrogenase]]
[[Category: Weizmannia coagulans]]
[[Category: Bacillus coagulans]]
[[Category: Fujita K]]
[[Category: Fujita, K.]]
[[Category: Minami H]]
[[Category: Minami, H.]]
[[Category: Mizui R]]
[[Category: Mizui, R.]]
[[Category: Nakamura S]]
[[Category: Nakamura, S.]]
[[Category: Sekiguchi T]]
[[Category: Sekiguchi, T.]]
[[Category: Suzuki K]]
[[Category: Suzuki, K.]]
[[Category: Takenaka A]]
[[Category: Takenaka, A.]]
[[Category: Tsunoda M]]
[[Category: Tsunoda, M.]]
[[Category: Tsuzaki S]]
[[Category: Tsuzaki, S.]]
[[Category: Bacillus coagulan]]
[[Category: Crystal structure]]
[[Category: Homo dimer]]
[[Category: Ipmdh]]
[[Category: Mutant]]
[[Category: S225a/e251l]]
[[Category: X-ray analysis]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 16:43:31 2009''
Retrieved from "https://proteopedia.org/1v5b"