2tec: Difference between revisions

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{{Seed}}
[[Image:2tec.png|left|200px]]


<!--
==MOLECULAR DYNAMICS REFINEMENT OF A THERMITASE-EGLIN-C COMPLEX AT 1.98 ANGSTROMS RESOLUTION AND COMPARISON OF TWO CRYSTAL FORMS THAT DIFFER IN CALCIUM CONTENT==
The line below this paragraph, containing "STRUCTURE_2tec", creates the "Structure Box" on the page.
<StructureSection load='2tec' size='340' side='right'caption='[[2tec]], [[Resolution|resolution]] 1.98&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2tec]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Poecilobdella_manillensis Poecilobdella manillensis] and [https://en.wikipedia.org/wiki/Thermoactinomyces_vulgaris Thermoactinomyces vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2TEC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2TEC FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.98&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
{{STRUCTURE_2tec| PDB=2tec |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2tec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2tec OCA], [https://pdbe.org/2tec PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2tec RCSB], [https://www.ebi.ac.uk/pdbsum/2tec PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2tec ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ICIC_HIRME ICIC_HIRME] Inhibits both elastase and cathepsin G.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/te/2tec_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2tec ConSurf].
<div style="clear:both"></div>


===MOLECULAR DYNAMICS REFINEMENT OF A THERMITASE-EGLIN-C COMPLEX AT 1.98 ANGSTROMS RESOLUTION AND COMPARISON OF TWO CRYSTAL FORMS THAT DIFFER IN CALCIUM CONTENT===
==See Also==
 
*[[Eglin|Eglin]]
 
__TOC__
<!--
</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_2689655}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 2689655 is the PubMed ID number.
[[Category: Poecilobdella manillensis]]
-->
{{ABSTRACT_PUBMED_2689655}}
 
==About this Structure==
2TEC is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Hirudinaria_manillensis Hirudinaria manillensis] and [http://en.wikipedia.org/wiki/Thermoactinomyces_vulgaris Thermoactinomyces vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2TEC OCA].
 
==Reference==
<ref group="xtra">PMID:2689655</ref><references group="xtra"/>
[[Category: Hirudinaria manillensis]]
[[Category: Thermitase]]
[[Category: Thermoactinomyces vulgaris]]
[[Category: Thermoactinomyces vulgaris]]
[[Category: Betzel, C.]]
[[Category: Betzel C]]
[[Category: Dauter, Z.]]
[[Category: Dauter Z]]
[[Category: Gros, P.]]
[[Category: Gros P]]
[[Category: Hol, W G.J.]]
[[Category: Hol WGJ]]
[[Category: Wilson, K S.]]
[[Category: Wilson KS]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:00:30 2009''
Retrieved from "https://proteopedia.org/2tec"