2f0d: Difference between revisions

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New page: left|200px<br /><applet load="2f0d" size="450" color="white" frame="true" align="right" spinBox="true" caption="2f0d, resolution 2.50Å" /> '''Crystal structure of...
 
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[[Image:2f0d.jpg|left|200px]]<br /><applet load="2f0d" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2f0d, resolution 2.50&Aring;" />
'''Crystal structure of Staphylococcal nuclease mutant I92V'''<br />


==About this Structure==
==Crystal structure of Staphylococcal nuclease mutant I92V==
2F0D is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Active as [http://en.wikipedia.org/wiki/Micrococcal_nuclease Micrococcal nuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.31.1 3.1.31.1] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2F0D OCA].  
<StructureSection load='2f0d' size='340' side='right'caption='[[2f0d]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
[[Category: Micrococcal nuclease]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[2f0d]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F0D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F0D FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f0d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f0d OCA], [https://pdbe.org/2f0d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f0d RCSB], [https://www.ebi.ac.uk/pdbsum/2f0d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f0d ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f0/2f0d_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f0d ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Staphylococcal nuclease 3D structures|Staphylococcal nuclease 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
[[Category: Lu, J.Z.]]
[[Category: Lu JZ]]
[[Category: Sakon, J.]]
[[Category: Sakon J]]
[[Category: Stites, W.E.]]
[[Category: Stites WE]]
[[Category: dna hydrolase; rna hydrolase; endonuclease; calcium; signal]]
 
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