1mcq: Difference between revisions

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{{Seed}}
[[Image:1mcq.png|left|200px]]


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==PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS==
The line below this paragraph, containing "STRUCTURE_1mcq", creates the "Structure Box" on the page.
<StructureSection load='1mcq' size='340' side='right'caption='[[1mcq]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1mcq]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MCQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MCQ FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=DPR:D-PROLINE'>DPR</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
{{STRUCTURE_1mcq|  PDB=1mcq  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mcq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mcq OCA], [https://pdbe.org/1mcq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mcq RCSB], [https://www.ebi.ac.uk/pdbsum/1mcq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mcq ProSAT]</span></td></tr>
 
</table>
===PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS===
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
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  <jmolCheckbox>
The line below this paragraph, {{ABSTRACT_PUBMED_8346191}}, adds the Publication Abstract to the page
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mc/1mcq_consurf.spt"</scriptWhenChecked>
(as it appears on PubMed at http://www.pubmed.gov), where 8346191 is the PubMed ID number.
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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    <text>to colour the structure by Evolutionary Conservation</text>
{{ABSTRACT_PUBMED_8346191}}
  </jmolCheckbox>
 
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mcq ConSurf].
==About this Structure==
<div style="clear:both"></div>
1MCQ is a 3 chains structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MCQ OCA].  
__TOC__
 
</StructureSection>
==Reference==
[[Category: Homo sapiens]]
<ref group="xtra">PMID:8346191</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Edmundson, A B.]]
[[Category: Edmundson AB]]
[[Category: Fan, Z C.]]
[[Category: Fan Z-C]]
[[Category: Guddat, L W.]]
[[Category: Guddat LW]]
[[Category: Harris, D L.]]
[[Category: Harris DL]]
[[Category: Immunoglobulin]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 18:04:15 2009''