2feo: Difference between revisions
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New page: left|200px<br /><applet load="2feo" size="450" color="white" frame="true" align="right" spinBox="true" caption="2feo, resolution 2.8Å" /> '''Mutant R188M of The C... |
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== | ==Mutant R188M of The Cytidine Monophosphate Kinase from E. coli complexed with dCMP== | ||
<StructureSection load='2feo' size='340' side='right'caption='[[2feo]], [[Resolution|resolution]] 2.80Å' scene=''> | |||
[[ | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2feo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FEO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FEO FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2feo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2feo OCA], [https://pdbe.org/2feo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2feo RCSB], [https://www.ebi.ac.uk/pdbsum/2feo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2feo ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/KCY_ECOLI KCY_ECOLI] ATP, dATP, and GTP are equally effective as phosphate donors. CMP and dCMP are the best phosphate acceptors.<ref>PMID:8190075</ref> <ref>PMID:7836281</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fe/2feo_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2feo ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Cytidine monophosphate kinase|Cytidine monophosphate kinase]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Alexov | [[Category: Alexov E]] | ||
[[Category: Barzu | [[Category: Barzu O]] | ||
[[Category: Bertrand | [[Category: Bertrand T]] | ||
[[Category: Briozzo | [[Category: Briozzo P]] | ||
[[Category: Bucurenci | [[Category: Bucurenci N]] | ||
[[Category: Gilles | [[Category: Gilles AM]] | ||
[[Category: Munier-Lehmann | [[Category: Munier-Lehmann H]] | ||
[[Category: Ofiteru | [[Category: Ofiteru A]] | ||
[[Category: Tourneux | [[Category: Tourneux L]] | ||
Latest revision as of 09:23, 14 February 2024
Mutant R188M of The Cytidine Monophosphate Kinase from E. coli complexed with dCMP
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