2fn3: Difference between revisions

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New page: left|200px<br /><applet load="2fn3" size="450" color="white" frame="true" align="right" spinBox="true" caption="2fn3, resolution 1.00Å" /> '''High resolution stru...
 
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[[Image:2fn3.jpg|left|200px]]<br /><applet load="2fn3" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2fn3, resolution 1.00&Aring;" />
'''High resolution structure of s26a mutant of benzoylformate decarboxylase from pseudomonas putida complexed with thiamine thiazolone diphosphate'''<br />


==About this Structure==
==High resolution structure of s26a mutant of benzoylformate decarboxylase from pseudomonas putida complexed with thiamine thiazolone diphosphate==
2FN3 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida] with MG, CA and TZD as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Benzoylformate_decarboxylase Benzoylformate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.7 4.1.1.7] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2FN3 OCA].  
<StructureSection load='2fn3' size='340' side='right'caption='[[2fn3]], [[Resolution|resolution]] 1.00&Aring;' scene=''>
[[Category: Benzoylformate decarboxylase]]
== Structural highlights ==
<table><tr><td colspan='2'>[[2fn3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FN3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FN3 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TZD:2-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-4-METHYL-2-OXO-2,3-DIHYDRO-1,3-THIAZOL-5-YL}ETHYL+TRIHYDROGEN+DIPHOSPHATE'>TZD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fn3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fn3 OCA], [https://pdbe.org/2fn3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fn3 RCSB], [https://www.ebi.ac.uk/pdbsum/2fn3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fn3 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MDLC_PSEPU MDLC_PSEPU]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fn/2fn3_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fn3 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pseudomonas putida]]
[[Category: Pseudomonas putida]]
[[Category: Single protein]]
[[Category: Bera AK]]
[[Category: Bera, A.K.]]
[[Category: Hasson MS]]
[[Category: Hasson, M.S.]]
[[Category: CA]]
[[Category: MG]]
[[Category: TZD]]
[[Category: carbon-carbon]]
[[Category: decarboxylase]]
[[Category: high resolution]]
[[Category: lyase]]
[[Category: mandelate catabolism]]
[[Category: thiamine thiazolone diphosphate]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 10:38:27 2007''