1m5y: Difference between revisions

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{{Seed}}
[[Image:1m5y.png|left|200px]]


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==Crystallographic Structure of SurA, a Molecular Chaperone that Facilitates Outer Membrane Porin Folding==
The line below this paragraph, containing "STRUCTURE_1m5y", creates the "Structure Box" on the page.
<StructureSection load='1m5y' size='340' side='right'caption='[[1m5y]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1m5y]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M5Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M5Y FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m5y OCA], [https://pdbe.org/1m5y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m5y RCSB], [https://www.ebi.ac.uk/pdbsum/1m5y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m5y ProSAT]</span></td></tr>
{{STRUCTURE_1m5y|  PDB=1m5y  |  SCENE=  }}
</table>
 
== Function ==
===Crystallographic Structure of SurA, a Molecular Chaperone that Facilitates Outer Membrane Porin Folding===
[https://www.uniprot.org/uniprot/SURA_ECOLI SURA_ECOLI] Chaperone involved in the correct folding and assembly of outer membrane proteins, such as OmpA, OmpF and LamB. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. Essential for the survival of E.coli in stationary phase. Required for pilus biogenesis.<ref>PMID:2165476</ref> <ref>PMID:8985185</ref> <ref>PMID:11226178</ref> <ref>PMID:16267292</ref>  
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m5/1m5y_consurf.spt"</scriptWhenChecked>
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    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_12429090}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
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==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m5y ConSurf].
1M5Y is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M5Y OCA].  
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== References ==
==Reference==
<references/>
<ref group="xtra">PMID:12429090</ref><references group="xtra"/>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Peptidylprolyl isomerase]]
[[Category: Large Structures]]
[[Category: Bitto, E.]]
[[Category: Bitto E]]
[[Category: McKay, D B.]]
[[Category: McKay DB]]
[[Category: Crystal structure]]
[[Category: Gram negative bacteria]]
[[Category: Membrane protein folding]]
[[Category: Periplasmic molecular chaperone]]
[[Category: Survival protein some]]
 
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