1uwc: Difference between revisions

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{{Seed}}
[[Image:1uwc.png|left|200px]]


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==Feruloyl esterase from Aspergillus niger==
The line below this paragraph, containing "STRUCTURE_1uwc", creates the "Structure Box" on the page.
<StructureSection load='1uwc' size='340' side='right'caption='[[1uwc]], [[Resolution|resolution]] 1.08&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1uwc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_niger Aspergillus niger]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UWC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UWC FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.08&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FER:3-(4-HYDROXY-3-METHOXYPHENYL)-2-PROPENOIC+ACID'>FER</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_1uwc|  PDB=1uwc  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uwc OCA], [https://pdbe.org/1uwc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uwc RCSB], [https://www.ebi.ac.uk/pdbsum/1uwc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uwc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FAEA_ASPNG FAEA_ASPNG] Involved in degradation of plant cell walls. Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans, and the feruloyl-galactose ester bond in pectin. Binds to cellulose.<ref>PMID:9406381</ref> <ref>PMID:11931668</ref> <ref>PMID:7805053</ref> <ref>PMID:9649839</ref> <ref>PMID:11931668</ref> <ref>PMID:15081808</ref> <ref>PMID:17027758</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uw/1uwc_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1uwc ConSurf].
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
The crystallographic structure of feruloyl esterase from Aspergillus niger has been determined to a resolution of 1.5 A by molecular replacement. The protein has an alpha/beta-hydrolase structure with a Ser-His-Asp catalytic triad; the overall fold of the protein is very similar to that of the fungal lipases. The structure of the enzyme-product complex was determined to a resolution of 1.08 A and reveals dual conformations for the serine and histidine residues at the active site.


===FERULOYL ESTERASE FROM ASPERGILLUS NIGER===
Structure of a feruloyl esterase from Aspergillus niger.,McAuley KE, Svendsen A, Patkar SA, Wilson KS Acta Crystallogr D Biol Crystallogr. 2004 May;60(Pt 5):878-87. Epub 2004, Apr 21. PMID:15103133<ref>PMID:15103133</ref>


 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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The line below this paragraph, {{ABSTRACT_PUBMED_15103133}}, adds the Publication Abstract to the page
<div class="pdbe-citations 1uwc" style="background-color:#fffaf0;"></div>
(as it appears on PubMed at http://www.pubmed.gov), where 15103133 is the PubMed ID number.
== References ==
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<references/>
{{ABSTRACT_PUBMED_15103133}}
__TOC__
 
</StructureSection>
==About this Structure==
1UWC is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Aspergillus_niger Aspergillus niger]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UWC OCA].
 
==Reference==
<ref group="xtra">PMID:15103133</ref><references group="xtra"/>
[[Category: Aspergillus niger]]
[[Category: Aspergillus niger]]
[[Category: Feruloyl esterase]]
[[Category: Large Structures]]
[[Category: Mcauley, K E.]]
[[Category: McAuley KE]]
[[Category: Patkar, S A.]]
[[Category: Patkar SA]]
[[Category: Svendsen, A.]]
[[Category: Svendsen A]]
[[Category: Wilson, K S.]]
[[Category: Wilson KS]]
[[Category: Hydrolase]]
[[Category: Serine esterase]]
[[Category: Xylan degradation]]
 
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Retrieved from "https://proteopedia.org/1uwc"