3dl2: Difference between revisions
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==Hexagonal structure of the LDH domain of Human Ubiquitin-conjugating Enzyme E2-like Isoform A== | |||
<StructureSection load='3dl2' size='340' side='right'caption='[[3dl2]], [[Resolution|resolution]] 2.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3dl2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DL2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DL2 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dl2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dl2 OCA], [https://pdbe.org/3dl2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dl2 RCSB], [https://www.ebi.ac.uk/pdbsum/3dl2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dl2 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/UEVLD_HUMAN UEVLD_HUMAN] Possible negative regulator of polyubiquitination.<ref>PMID:12427560</ref> | |||
== Evolutionary Conservation == | |||
== | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | |||
<jmolCheckbox> | |||
== | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dl/3dl2_consurf.spt"</scriptWhenChecked> | ||
< | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dl2 ConSurf]. | |||
<div style="clear:both"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Arrowsmith | [[Category: Large Structures]] | ||
[[Category: Avvakumov | [[Category: Arrowsmith CH]] | ||
[[Category: Bochkarev | [[Category: Avvakumov GV]] | ||
[[Category: Bountra | [[Category: Bochkarev A]] | ||
[[Category: Butler-Cole | [[Category: Bountra C]] | ||
[[Category: Dhe-Paganon | [[Category: Butler-Cole C]] | ||
[[Category: Edwards | [[Category: Dhe-Paganon S]] | ||
[[Category: Jr | [[Category: Edwards AM]] | ||
[[Category: Newman | [[Category: Finerty Jr PJ]] | ||
[[Category: Newman EM]] | |||
[[Category: Walker | [[Category: Walker JR]] | ||
[[Category: Wolkstrom | [[Category: Wolkstrom M]] | ||
[[Category: Xue | [[Category: Xue S]] | ||