2g82: Difference between revisions

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New page: left|200px<br /><applet load="2g82" size="450" color="white" frame="true" align="right" spinBox="true" caption="2g82, resolution 1.650Å" /> '''High Resolution Str...
 
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[[Image:2g82.jpg|left|200px]]<br /><applet load="2g82" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2g82, resolution 1.650&Aring;" />
'''High Resolution Structures of Thermus aquaticus Glyceraldehyde-3-Phosphate Dehydrogenase: Role of 220's Loop Motion in Catalysis'''<br />


==About this Structure==
==High Resolution Structures of Thermus aquaticus Glyceraldehyde-3-Phosphate Dehydrogenase: Role of 220's Loop Motion in Catalysis==
2G82 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus] with NA, NAD, PGE, IPA and GOL as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Glyceraldehyde-3-phosphate_dehydrogenase_(phosphorylating) Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.12 1.2.1.12] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2G82 OCA].  
<StructureSection load='2g82' size='340' side='right'caption='[[2g82]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
[[Category: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[2g82]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G82 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G82 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g82 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g82 OCA], [https://pdbe.org/2g82 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g82 RCSB], [https://www.ebi.ac.uk/pdbsum/2g82 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g82 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/G3P_THEAQ G3P_THEAQ]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g8/2g82_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2g82 ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Aldehyde dehydrogenase 3D structures|Aldehyde dehydrogenase 3D structures]]
*[[Glyceraldehyde-3-phosphate dehydrogenase 3D structures|Glyceraldehyde-3-phosphate dehydrogenase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermus aquaticus]]
[[Category: Thermus aquaticus]]
[[Category: Buencamino, R.]]
[[Category: Buencamino R]]
[[Category: Jenkins, J.L.]]
[[Category: Jenkins JL]]
[[Category: Tanner, J.J.]]
[[Category: Tanner JJ]]
[[Category: GOL]]
[[Category: IPA]]
[[Category: NA]]
[[Category: NAD]]
[[Category: PGE]]
[[Category: g3pdh]]
[[Category: gapdh]]
[[Category: glycolysis]]
[[Category: nad]]
[[Category: oxidoreductase]]
[[Category: rossmann fold]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 11:01:14 2007''

Latest revision as of 08:02, 30 October 2024

High Resolution Structures of Thermus aquaticus Glyceraldehyde-3-Phosphate Dehydrogenase: Role of 220's Loop Motion in Catalysis

2g82, resolution 1.65Å

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