2dpm: Difference between revisions

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{{Seed}}
[[Image:2dpm.png|left|200px]]


<!--
==DPNM DNA ADENINE METHYLTRANSFERASE FROM STREPTOCCOCUS PNEUMONIAE COMPLEXED WITH S-ADENOSYLMETHIONINE==
The line below this paragraph, containing "STRUCTURE_2dpm", creates the "Structure Box" on the page.
<StructureSection load='2dpm' size='340' side='right'caption='[[2dpm]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2dpm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DPM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DPM FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
{{STRUCTURE_2dpm|  PDB=2dpm  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dpm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dpm OCA], [https://pdbe.org/2dpm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dpm RCSB], [https://www.ebi.ac.uk/pdbsum/2dpm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dpm ProSAT]</span></td></tr>
 
</table>
===DPNM DNA ADENINE METHYLTRANSFERASE FROM STREPTOCCOCUS PNEUMONIAE COMPLEXED WITH S-ADENOSYLMETHIONINE===
== Function ==
 
[https://www.uniprot.org/uniprot/MTD21_STREE MTD21_STREE] This methylase recognizes the double-stranded sequence GATC, causes specific methylation on A-2 on both strands, and protects the DNA from cleavage by the DpnII endonuclease.
 
== Evolutionary Conservation ==
<!--
[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_9862809}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 9862809 is the PubMed ID number.
  <jmolCheckbox>
-->
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dp/2dpm_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_9862809}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
2DPM is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DPM OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dpm ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
<ref group="xtra">PMID:9862809</ref><references group="xtra"/>
</StructureSection>
[[Category: Large Structures]]
[[Category: Streptococcus pneumoniae]]
[[Category: Streptococcus pneumoniae]]
[[Category: Cerritelli, S.]]
[[Category: Cerritelli S]]
[[Category: Korszun, Z R.]]
[[Category: Korszun ZR]]
[[Category: Lacks, S A.]]
[[Category: Lacks SA]]
[[Category: Springhorn, S S.]]
[[Category: Springhorn SS]]
[[Category: Tran, P H.]]
[[Category: Tran PH]]
[[Category: Dna adenine methyltransferase]]
[[Category: Dna methyltransferase group alpha]]
[[Category: Dna n6-adenine methylation]]
[[Category: Dpnii restriction-modification system]]
[[Category: Gatc methylation]]
[[Category: Methylase]]
[[Category: Methyltransferase]]
[[Category: Rossman fold]]
[[Category: S-adenosylmethionine]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 00:18:53 2009''

Latest revision as of 09:18, 14 February 2024

DPNM DNA ADENINE METHYLTRANSFERASE FROM STREPTOCCOCUS PNEUMONIAE COMPLEXED WITH S-ADENOSYLMETHIONINE

2dpm, resolution 1.80Å

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