1lru: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
 
(8 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{Seed}}
[[Image:1lru.png|left|200px]]


<!--
==Crystal Structure of E.coli Peptide Deformylase Complexed with Antibiotic Actinonin==
The line below this paragraph, containing "STRUCTURE_1lru", creates the "Structure Box" on the page.
<StructureSection load='1lru' size='340' side='right'caption='[[1lru]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1lru]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LRU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LRU FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BB2:ACTINONIN'>BB2</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_1lru|  PDB=1lru  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lru FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lru OCA], [https://pdbe.org/1lru PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lru RCSB], [https://www.ebi.ac.uk/pdbsum/1lru PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lru ProSAT]</span></td></tr>
 
</table>
===Crystal Structure of E.coli Peptide Deformylase Complexed with Antibiotic Actinonin===
== Function ==
 
[https://www.uniprot.org/uniprot/DEF_ECOLI DEF_ECOLI] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.[HAMAP-Rule:MF_00163]
 
== Evolutionary Conservation ==
<!--
[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_12126617}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 12126617 is the PubMed ID number.
  <jmolCheckbox>
-->
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lr/1lru_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_12126617}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1LRU is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LRU OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lru ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
<ref group="xtra">PMID:12126617</ref><references group="xtra"/>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Peptide deformylase]]
[[Category: Large Structures]]
[[Category: Blanc, V.]]
[[Category: Blanc V]]
[[Category: Chevrier, M.]]
[[Category: Chevrier M]]
[[Category: Dupuy, A.]]
[[Category: Dupuy A]]
[[Category: Famechon, A.]]
[[Category: Famechon A]]
[[Category: Giglione, C.]]
[[Category: Giglione C]]
[[Category: Gil, P.]]
[[Category: Gil P]]
[[Category: Guilloteau, J P.]]
[[Category: Guilloteau J-P]]
[[Category: Mathieu, M.]]
[[Category: Mathieu M]]
[[Category: Meinnel, T.]]
[[Category: Meinnel T]]
[[Category: Mikol, V.]]
[[Category: Mikol V]]
[[Category: Actinonin]]
[[Category: Inhibition]]
[[Category: Polypeptide deformylase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 00:28:24 2009''
Retrieved from "https://proteopedia.org/1lru"