1wtj: Difference between revisions

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{{Seed}}
[[Image:1wtj.png|left|200px]]


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==Crystal Structure of delta1-piperideine-2-carboxylate reductase from Pseudomonas syringae pvar.tomato==
The line below this paragraph, containing "STRUCTURE_1wtj", creates the "Structure Box" on the page.
<StructureSection load='1wtj' size='340' side='right'caption='[[1wtj]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1wtj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_syringae_pv._tomato Pseudomonas syringae pv. tomato]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WTJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WTJ FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wtj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wtj OCA], [https://pdbe.org/1wtj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wtj RCSB], [https://www.ebi.ac.uk/pdbsum/1wtj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wtj ProSAT]</span></td></tr>
{{STRUCTURE_1wtj|  PDB=1wtj  |  SCENE=  }}
</table>
 
== Function ==
===Crystal Structure of delta1-piperideine-2-carboxylate reductase from Pseudomonas syringae pvar.tomato===
[https://www.uniprot.org/uniprot/PY2CR_PSEUB PY2CR_PSEUB] Catalyzes the reduction of both Delta(1)-pyrroline-2-carboxylate (Pyr2C) and Delta(1)-piperideine-2-carboxylate (Pip2C) to L-proline and L-pipecolate, respectively, using NADPH as the electron donor. Can catalyze the reverse oxidation reactions, albeit at a much lower rate. Is also able to catalyze in vitro the NADPH-dependent formation of N-methylalanine from pyruvate and N-methylamine; can act on other alpha-keto acids and specifically uses methylamine and not ammonia for these reductive amination reactions. Can use NADH instead of NADPH, although with much less efficiency.<ref>PMID:16192274</ref>  
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wt/1wtj_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_16192274}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wtj ConSurf].
1WTJ is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Pseudomonas_syringae_pv._tomato Pseudomonas syringae pv. tomato]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WTJ OCA].  
<div style="clear:both"></div>
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:16192274</ref><references group="xtra"/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pseudomonas syringae pv. tomato]]
[[Category: Pseudomonas syringae pv. tomato]]
[[Category: Ureidoglycolate dehydrogenase]]
[[Category: Esaki N]]
[[Category: Esaki, N.]]
[[Category: Goto M]]
[[Category: Goto, M.]]
[[Category: Hirotsu K]]
[[Category: Hirotsu, K.]]
[[Category: Kurihara T]]
[[Category: Kurihara, T.]]
[[Category: Mihara H]]
[[Category: Mihara, H.]]
[[Category: Miyahara I]]
[[Category: Miyahara, I.]]
[[Category: Muramatsu H]]
[[Category: Muramatsu, H.]]
[[Category: Omi R]]
[[Category: Omi, R.]]
[[Category: Nadph dependent enzyme]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 02:04:36 2009''
Retrieved from "https://proteopedia.org/1wtj"