2b6h: Difference between revisions

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{{Seed}}
[[Image:2b6h.png|left|200px]]


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==Structure of human ADP-ribosylation factor 5==
The line below this paragraph, containing "STRUCTURE_2b6h", creates the "Structure Box" on the page.
<StructureSection load='2b6h' size='340' side='right'caption='[[2b6h]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2b6h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B6H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B6H FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.764&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
{{STRUCTURE_2b6h|  PDB=2b6h  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b6h OCA], [https://pdbe.org/2b6h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b6h RCSB], [https://www.ebi.ac.uk/pdbsum/2b6h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b6h ProSAT]</span></td></tr>
 
</table>
===Structure of human ADP-ribosylation factor 5===
== Function ==
 
[https://www.uniprot.org/uniprot/ARF5_HUMAN ARF5_HUMAN] GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
2B6H is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B6H OCA].  
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b6/2b6h_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b6h ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C.]]
[[Category: Large Structures]]
[[Category: Atanassova, A.]]
[[Category: Arrowsmith C]]
[[Category: Bochkarev, A.]]
[[Category: Atanassova A]]
[[Category: Dimov, S.]]
[[Category: Bochkarev A]]
[[Category: Edwards, A.]]
[[Category: Dimov S]]
[[Category: Lew, J.]]
[[Category: Edwards A]]
[[Category: Park, H.]]
[[Category: Lew J]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Park H]]
[[Category: Shehab, I.]]
[[Category: Shehab I]]
[[Category: Sundarajan, E.]]
[[Category: Sundarajan E]]
[[Category: Sundstrom, M.]]
[[Category: Sundstrom M]]
[[Category: Tempel, W.]]
[[Category: Tempel W]]
[[Category: Weigelt, J.]]
[[Category: Weigelt J]]
[[Category: Gdp]]
[[Category: Membrane trafficking]]
[[Category: Sgc]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 02:55:17 2009''