1yvf: Difference between revisions

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{{Seed}}
[[Image:1yvf.png|left|200px]]


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==Hepatitis C virus NS5B RNA-dependent RNA polymerase complex with inhibitor PHA-00729145==
The line below this paragraph, containing "STRUCTURE_1yvf", creates the "Structure Box" on the page.
<StructureSection load='1yvf' size='340' side='right'caption='[[1yvf]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1yvf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepacivirus_C Hepacivirus C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YVF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YVF FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PH7:(2Z)-2-(BENZOYLAMINO)-3-[4-(2-BROMOPHENOXY)PHENYL]-2-PROPENOIC+ACID'>PH7</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
{{STRUCTURE_1yvf|  PDB=1yvf  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yvf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yvf OCA], [https://pdbe.org/1yvf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yvf RCSB], [https://www.ebi.ac.uk/pdbsum/1yvf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yvf ProSAT]</span></td></tr>
 
</table>
===Hepatitis C virus NS5B RNA-dependent RNA polymerase complex with inhibitor PHA-00729145===
== Function ==
 
[https://www.uniprot.org/uniprot/O93077_9HEPC O93077_9HEPC]  
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_15863301}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 15863301 is the PubMed ID number.
  <jmolCheckbox>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yv/1yvf_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_15863301}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1YVF is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YVF OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yvf ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
<ref group="xtra">PMID:15863301</ref><references group="xtra"/>
</StructureSection>
[[Category: Hepatitis c virus]]
[[Category: Hepacivirus C]]
[[Category: RNA-directed RNA polymerase]]
[[Category: Large Structures]]
[[Category: Anstadt, R A.]]
[[Category: Anstadt RA]]
[[Category: Finzel, B C.]]
[[Category: Finzel BC]]
[[Category: Greene, M L.]]
[[Category: Greene ML]]
[[Category: Gross, R J.]]
[[Category: Gross RJ]]
[[Category: Harris, M S.]]
[[Category: Harris MS]]
[[Category: Kilkuskie, R E.]]
[[Category: Kilkuskie RE]]
[[Category: Kopta, L A.]]
[[Category: Kopta LA]]
[[Category: Mitchell, M A.]]
[[Category: Mitchell MA]]
[[Category: Nugent, R A.]]
[[Category: Nugent RA]]
[[Category: Pfefferkorn, J A.]]
[[Category: Pfefferkorn JA]]
[[Category: Schwende, F J.]]
[[Category: Schwende FJ]]
[[Category: Shelly, J A.]]
[[Category: Shelly JA]]
[[Category: Wells, P A.]]
[[Category: Wells PA]]
[[Category: Finger]]
[[Category: Hcv]]
[[Category: Ns5b]]
[[Category: Palm]]
[[Category: Polymerase]]
[[Category: Thumb]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 03:02:45 2009''