1kta: Difference between revisions

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{{Seed}}
[[Image:1kta.png|left|200px]]


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==HUMAN BRANCHED CHAIN AMINO ACID AMINOTRANSFERASE : THREE DIMENSIONAL STRUCTURE OF THE ENZYME IN ITS PYRIDOXAMINE PHOSPHATE FORM.==
The line below this paragraph, containing "STRUCTURE_1kta", creates the "Structure Box" on the page.
<StructureSection load='1kta' size='340' side='right'caption='[[1kta]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1kta]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KTA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KTA FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KIV:3-METHYL-2-OXOBUTANOIC+ACID'>KIV</scene>, <scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene></td></tr>
{{STRUCTURE_1kta| PDB=1kta |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kta OCA], [https://pdbe.org/1kta PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kta RCSB], [https://www.ebi.ac.uk/pdbsum/1kta PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kta ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BCAT2_HUMAN BCAT2_HUMAN] Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kt/1kta_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kta ConSurf].
<div style="clear:both"></div>


===HUMAN BRANCHED CHAIN AMINO ACID AMINOTRANSFERASE : THREE DIMENSIONAL STRUCTURE OF THE ENZYME IN ITS PYRIDOXAMINE PHOSPHATE FORM.===
==See Also==
 
*[[Aminotransferase 3D structures|Aminotransferase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_12269802}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 12269802 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12269802}}
 
==About this Structure==
1KTA is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KTA OCA].
 
==Reference==
<ref group="xtra">PMID:12269802</ref><references group="xtra"/>
[[Category: Branched-chain-amino-acid transaminase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Conway, M E.]]
[[Category: Large Structures]]
[[Category: Farber, G K.]]
[[Category: Conway ME]]
[[Category: Hutson, S M.]]
[[Category: Farber GK]]
[[Category: Yennawar, H P.]]
[[Category: Hutson SM]]
[[Category: Yennawar, N H.]]
[[Category: Yennawar HP]]
[[Category: Fold type iv]]
[[Category: Yennawar NH]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 04:01:55 2009''

Latest revision as of 07:27, 14 February 2024

HUMAN BRANCHED CHAIN AMINO ACID AMINOTRANSFERASE : THREE DIMENSIONAL STRUCTURE OF THE ENZYME IN ITS PYRIDOXAMINE PHOSPHATE FORM.

1kta, resolution 1.90Å

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