3bji: Difference between revisions

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{{Seed}}
[[Image:3bji.png|left|200px]]


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==Structural Basis of Promiscuous Guanine Nucleotide Exchange by the T-Cell Essential Vav1==
The line below this paragraph, containing "STRUCTURE_3bji", creates the "Structure Box" on the page.
<StructureSection load='3bji' size='340' side='right'caption='[[3bji]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3bji]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BJI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BJI FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_3bji| PDB=3bji |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bji FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bji OCA], [https://pdbe.org/3bji PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bji RCSB], [https://www.ebi.ac.uk/pdbsum/3bji PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bji ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/VAV_HUMAN VAV_HUMAN] Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bj/3bji_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3bji ConSurf].
<div style="clear:both"></div>


===Structural Basis of Promiscuous Guanine Nucleotide Exchange by the T-Cell Essential Vav1===
==See Also==
 
*[[Rac 3D structures|Rac 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_18589439}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 18589439 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_18589439}}
 
==About this Structure==
3BJI is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BJI OCA].
 
==Reference==
<ref group="xtra">PMID:18589439</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Brooun, A.]]
[[Category: Large Structures]]
[[Category: Chrencik, J E.]]
[[Category: Brooun A]]
[[Category: Kuhn, P.]]
[[Category: Chrencik JE]]
[[Category: Adp-ribosylation]]
[[Category: Kuhn P]]
[[Category: Alternative splicing]]
[[Category: Atypical cysteine rich domain]]
[[Category: Gef/gtpase]]
[[Category: Gtp-binding]]
[[Category: Guanine-nucleotide releasing factor]]
[[Category: Lipoprotein]]
[[Category: Membrane]]
[[Category: Metal-binding]]
[[Category: Methylation]]
[[Category: Nucleotide-binding]]
[[Category: Phorbol-ester binding]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Prenylation]]
[[Category: Protein-protein interaction]]
[[Category: Proto-oncogene]]
[[Category: Sh2 domain]]
[[Category: Sh3 domain]]
[[Category: Signaling protein]]
[[Category: Zinc]]
[[Category: Zinc-finger]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 04:06:24 2009''
Retrieved from "https://proteopedia.org/3bji"