2b3t: Difference between revisions

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{{Seed}}
[[Image:2b3t.png|left|200px]]


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==Structure of complex between E. coli translation termination factor RF1 and the PrmC methyltransferase==
The line below this paragraph, containing "STRUCTURE_2b3t", creates the "Structure Box" on the page.
<StructureSection load='2b3t' size='340' side='right'caption='[[2b3t]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2b3t]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B3T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B3T FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
{{STRUCTURE_2b3t|  PDB=2b3t  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b3t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b3t OCA], [https://pdbe.org/2b3t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b3t RCSB], [https://www.ebi.ac.uk/pdbsum/2b3t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b3t ProSAT]</span></td></tr>
 
</table>
===Molecular basis for bacterial class 1 release factor methylation by PrmC===
== Function ==
 
[https://www.uniprot.org/uniprot/PRMC_ECOLI PRMC_ECOLI] Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif, i.e. on 'Gln-235' in RF1 and on 'Gln-252' in RF2.<ref>PMID:11805295</ref> <ref>PMID:11847124</ref> <ref>PMID:16364916</ref>  
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b3/2b3t_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_16364916}}
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    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
2B3T is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B3T OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b3t ConSurf].
 
<div style="clear:both"></div>
==Reference==
== References ==
<ref group="xtra">PMID:16364916</ref><references group="xtra"/>
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Buckingham, R H.]]
[[Category: Large Structures]]
[[Category: Champ, S.]]
[[Category: Buckingham RH]]
[[Category: Graille, M.]]
[[Category: Champ S]]
[[Category: Heurgue-Hamard, V.]]
[[Category: Graille M]]
[[Category: Mora, L.]]
[[Category: Heurgue-Hamard V]]
[[Category: Scrima, N.]]
[[Category: Mora L]]
[[Category: Tilbeurgh, H van.]]
[[Category: Scrima N]]
[[Category: Ulryck, N.]]
[[Category: Ulryck N]]
[[Category: Conformational change]]
[[Category: Van Tilbeurgh H]]
[[Category: Methylation]]
[[Category: Release factor]]
[[Category: Translation termination]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 04:21:38 2009''

Latest revision as of 09:15, 14 February 2024

Structure of complex between E. coli translation termination factor RF1 and the PrmC methyltransferase

2b3t, resolution 3.10Å

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