1hi4: Difference between revisions

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{{Seed}}
[[Image:1hi4.png|left|200px]]


<!--
==Eosinophil-derived Neurotoxin (EDN) - Adenosien-3'-5'-Diphosphate Complex==
The line below this paragraph, containing "STRUCTURE_1hi4", creates the "Structure Box" on the page.
<StructureSection load='1hi4' size='340' side='right'caption='[[1hi4]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1hi4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HI4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HI4 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A3P:ADENOSINE-3-5-DIPHOSPHATE'>A3P</scene></td></tr>
{{STRUCTURE_1hi4|  PDB=1hi4  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hi4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hi4 OCA], [https://pdbe.org/1hi4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hi4 RCSB], [https://www.ebi.ac.uk/pdbsum/1hi4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hi4 ProSAT]</span></td></tr>
 
</table>
===EOSINOPHIL-DERIVED NEUROTOXIN (EDN)-ADENOSINE-3'-5'-DIPHOSPHATE COMPLEX===
== Function ==
 
[https://www.uniprot.org/uniprot/RNAS2_HUMAN RNAS2_HUMAN] This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities.<ref>PMID:3458170</ref> <ref>PMID:12578357</ref>  
 
== Evolutionary Conservation ==
<!--
[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_11154698}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 11154698 is the PubMed ID number.
  <jmolCheckbox>
-->
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hi/1hi4_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_11154698}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1HI4 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HI4 OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hi4 ConSurf].
 
<div style="clear:both"></div>
==Reference==
== References ==
<ref group="xtra">PMID:11154698</ref><references group="xtra"/>
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Pancreatic ribonuclease]]
[[Category: Large Structures]]
[[Category: Acharya, K R.]]
[[Category: Acharya KR]]
[[Category: Boix, E.]]
[[Category: Boix E]]
[[Category: Leonidas, D D.]]
[[Category: Leonidas DD]]
[[Category: Minson, K.]]
[[Category: Minson K]]
[[Category: Prill, R.]]
[[Category: Prill R]]
[[Category: Suzuki, M.]]
[[Category: Suzuki M]]
[[Category: Swaminathan, G J.]]
[[Category: Swaminathan GJ]]
[[Category: Turton, R.]]
[[Category: Turton R]]
[[Category: Youle, R J.]]
[[Category: Youle RJ]]
[[Category: Ribonuclease]]
[[Category: Rnase us]]
[[Category: Rnase-2]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 07:10:54 2009''
Retrieved from "https://proteopedia.org/1hi4"