3g1l: Difference between revisions
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New page: '''Unreleased structure''' The entry 3g1l is ON HOLD Authors: Willand, N., Dirie, B., Carette, X., Bifani, P., Singhal, A., Desroses, M., Leroux, F., Willery, E., Mathys, V., Deprez-Pou... |
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==EthR from Mycobacterium tuberculosis in complex with compound BDM14744== | |||
<StructureSection load='3g1l' size='340' side='right'caption='[[3g1l]], [[Resolution|resolution]] 1.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3g1l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G1L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3G1L FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=RF2:3-(4-FLUOROPHENYL)-5-PHENYL-4H-1,2,4-TRIAZOLE'>RF2</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3g1l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g1l OCA], [https://pdbe.org/3g1l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3g1l RCSB], [https://www.ebi.ac.uk/pdbsum/3g1l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3g1l ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g1/3g1l_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3g1l ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mycobacterium tuberculosis]] | |||
[[Category: Aumercier M]] | |||
[[Category: Baulard AR]] | |||
[[Category: Bifani P]] | |||
[[Category: Carette X]] | |||
[[Category: Delcroix G]] | |||
[[Category: Deprez B]] | |||
[[Category: Deprez-Poulain R]] | |||
[[Category: Desroses M]] | |||
[[Category: Dirie B]] | |||
[[Category: Frenois F]] | |||
[[Category: Leroux F]] | |||
[[Category: Locht C]] | |||
[[Category: Mathys V]] | |||
[[Category: Singhal A]] | |||
[[Category: Villeret V]] | |||
[[Category: Willand N]] | |||
[[Category: Willery E]] | |||
Latest revision as of 09:51, 21 February 2024
EthR from Mycobacterium tuberculosis in complex with compound BDM14744
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