1bm8: Difference between revisions

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{{Seed}}
[[Image:1bm8.png|left|200px]]


<!--
==DNA-BINDING DOMAIN OF MBP1==
The line below this paragraph, containing "STRUCTURE_1bm8", creates the "Structure Box" on the page.
<StructureSection load='1bm8' size='340' side='right'caption='[[1bm8]], [[Resolution|resolution]] 1.71&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1bm8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BM8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BM8 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.71&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bm8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bm8 OCA], [https://pdbe.org/1bm8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bm8 RCSB], [https://www.ebi.ac.uk/pdbsum/1bm8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bm8 ProSAT]</span></td></tr>
{{STRUCTURE_1bm8|  PDB=1bm8  |  SCENE=  }}
</table>
 
== Function ==
===DNA-BINDING DOMAIN OF MBP1===
[https://www.uniprot.org/uniprot/MBP1_YEAST MBP1_YEAST] Binds to MCB elements (Mlu I cell cycle box) found in the promoter of most DNA synthesis genes. Transcriptional activation by MBF has an important role in the transition from G1 to S phase. It may have a dual role in that it behaves as an activator of transcription at the G1-S boundary and as a repressor during other stages of the cell cycle.
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
<!--
Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_9083114}}, adds the Publication Abstract to the page
  <jmolCheckbox>
(as it appears on PubMed at http://www.pubmed.gov), where 9083114 is the PubMed ID number.
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bm/1bm8_consurf.spt"</scriptWhenChecked>
-->
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_9083114}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bm8 ConSurf].
1BM8 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BM8 OCA].  
<div style="clear:both"></div>
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:9083114</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Cheng, X.]]
[[Category: Cheng X]]
[[Category: Horton, J R.]]
[[Category: Horton JR]]
[[Category: Knapp, D.]]
[[Category: Knapp D]]
[[Category: Koch, C.]]
[[Category: Koch C]]
[[Category: Liu, Y.]]
[[Category: Liu Y]]
[[Category: Nasmyth, K.]]
[[Category: Nasmyth K]]
[[Category: Xu, R M.]]
[[Category: Xu R-M]]
[[Category: Cell cycle]]
[[Category: Cyclin]]
[[Category: Dna synthesis]]
[[Category: Helix-turn-helix dna-binding domain]]
[[Category: Multiwavelength anomalous diffraction]]
[[Category: Transcription factor]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:02:00 2009''
Retrieved from "https://proteopedia.org/1bm8"