2i8a: Difference between revisions

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New page: left|200px<br /><applet load="2i8a" size="450" color="white" frame="true" align="right" spinBox="true" caption="2i8a, resolution 1.64Å" /> '''Salmonella typhimuri...
 
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[[Image:2i8a.jpg|left|200px]]<br /><applet load="2i8a" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2i8a, resolution 1.64&Aring;" />
'''Salmonella typhimurium liganded by phosphate ion at 1.64A resolution'''<br />


==About this Structure==
==Salmonella typhimurium liganded by phosphate ion at 1.64A resolution==
2I8A is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium] with PO4 as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Uridine_phosphorylase Uridine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.3 2.4.2.3] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2I8A OCA].  
<StructureSection load='2i8a' size='340' side='right'caption='[[2i8a]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
[[Category: Salmonella typhimurium]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[2i8a]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I8A FirstGlance]. <br>
[[Category: Uridine phosphorylase]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.64&#8491;</td></tr>
[[Category: Gabdoulkhakov, A.G.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
[[Category: Mikhailov, A.M.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i8a OCA], [https://pdbe.org/2i8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i8a RCSB], [https://www.ebi.ac.uk/pdbsum/2i8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i8a ProSAT]</span></td></tr>
[[Category: Timofeev, V.I.]]
</table>
[[Category: PO4]]
== Function ==
[[Category: nucleoside phosphorylase]]
[https://www.uniprot.org/uniprot/UDP_SALTY UDP_SALTY] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity).
[[Category: transferase]]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i8/2i8a_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i8a ConSurf].
<div style="clear:both"></div>


''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 12:11:28 2007''
==See Also==
*[[Uridine phosphorylase 3D structures|Uridine phosphorylase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
[[Category: Gabdoulkhakov AG]]
[[Category: Mikhailov AM]]
[[Category: Timofeev VI]]
Retrieved from "https://proteopedia.org/2i8a"