1rpl: Difference between revisions

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~~{{Seed}}~~

~~[[Image:1rpl.png|left|200px]]~~

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==2.3 ANGSTROMS CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF DNA POLYMERASE BETA==

~~The line below this paragraph, containing~~ "~~STRUCTURE_1rpl~~"~~, creates the~~ "~~Structure Box~~" ~~on the page~~.

~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)

== Structural highlights ==

or the ~~SCENE parameter (which sets~~ the ~~initial scene displayed when~~ the ~~page is loaded),~~

<table><tr><td colspan='2'>[[1rpl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RPL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RPL FirstGlance]. <br>

~~or leave~~ the ~~SCENE parameter empty for the default display.~~

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr>

-->

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rpl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rpl OCA], [https://pdbe.org/1rpl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rpl RCSB], [https://www.ebi.ac.uk/pdbsum/1rpl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rpl ProSAT]</span></td></tr>

~~{{STRUCTURE_1rpl~~| ~~PDB~~=1rpl ~~| SCENE~~= }}

</table>

== Function ==

[https://www.uniprot.org/uniprot/DPOLB_RAT DPOLB_RAT] Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

== Evolutionary Conservation ==

[[Image:Consurf_key_small.gif|200px|right]]

Check<jmol>

<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rp/1rpl_consurf.spt"</scriptWhenChecked>

<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>

<text>to colour the structure by Evolutionary Conservation</text>

</jmolCheckbox>

</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rpl ConSurf].

==~~=2.3 ANGSTROMS CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF DNA POLYMERASE BETA=~~==

==See Also==

*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]

__TOC__

<~~!--~~

</StructureSection>

~~The line below this paragraph, {{ABSTRACT_PUBMED_8137427}}, adds the Publication Abstract to the page~~

[[Category: Large Structures]]

~~(as it appears on PubMed at http:/~~/~~www.pubmed.gov), where 8137427 is the PubMed ID number.~~

-->

~~{{ABSTRACT_PUBMED_8137427}}~~

~~==About this Structure==~~

~~1RPL is a 1 chain structure of sequence from~~ [~~http~~:~~//en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus~~]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RPL OCA~~].

~~==Reference==~~

~~<ref group="xtra">PMID:8137427</ref><references group="xtra"/>~~

[[Category: Rattus norvegicus]]

[[Category: Almassy~~, R J.~~]]

[[Category: Almassy RJ]]

[[Category: II~~, J F.Davies.]]~~

[[Category: Davies II JF]]

~~[[Category: Nucleotidyltransferase]~~]

~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA~~ ] ~~on Wed Feb 18 09:49:53 2009''~~

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@@ Line 1: / Line 1: @@
-{{Seed}}
-[[Image:1rpl.png|left|200px]]
-<!--
+==2.3 ANGSTROMS CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF DNA POLYMERASE BETA==
-The line below this paragraph, containing "STRUCTURE_1rpl", creates the "Structure Box" on the page.
+<StructureSection load='1rpl' size='340' side='right'caption='[[1rpl]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1rpl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RPL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RPL FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rpl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rpl OCA], [https://pdbe.org/1rpl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rpl RCSB], [https://www.ebi.ac.uk/pdbsum/1rpl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rpl ProSAT]</span></td></tr>
-{{STRUCTURE_1rpl|  PDB=1rpl  |  SCENE=  }}
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/DPOLB_RAT DPOLB_RAT] Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rp/1rpl_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rpl ConSurf].
+<div style="clear:both"></div>
-===2.3 ANGSTROMS CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF DNA POLYMERASE BETA===
+==See Also==
+*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_8137427}}, adds the Publication Abstract to the page
+[[Category: Large Structures]]
-(as it appears on PubMed at http://www.pubmed.gov), where 8137427 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_8137427}}
-==About this Structure==
-RPL is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RPL OCA].
-==Reference==
-<ref group="xtra">PMID:8137427</ref><references group="xtra"/>
 [[Category: Rattus norvegicus]]
-[[Category: Almassy, R J.]]
+[[Category: Almassy RJ]]
-[[Category: II, J F.Davies.]]
+[[Category: Davies II JF]]
-[[Category: Nucleotidyltransferase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:49:53 2009''