Sandbox4: Difference between revisions

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Name: Jamal Salah

Name: Jamal Salah and Vishwa Shah!

Vishwa Shah

LKT:

It's alpha and beta SUBUNITS (2 of each). Say something about the secondary elements (ie 5 alpha helices and 2 beta strands)

I see problems with greek letters on the JMol, so best to write out alpha and beta. Why did you highlight His which is not hydrophobic?

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== '''~~Deoxyhaemoglobin~~''' ==

== '''Deoxyhemoglobin''' ==

The major oxygen-binding molecule in man, responsible for binding oxygen in the lung and transporting it to the tissues by means of circulation.

~~Haemoglobin (Hb)~~ is an iron Fe chelate tightly binding one Fe ~~ion in its II oxidation state~~ where it carries ~~the charge~~ 2+(ferrous ion). If no oxygen molecule is bound it is called ~~deoxyhaemoglobin~~.~~Deoxyhaemoglobin~~ is a tetramer of ~~two α~~ and ~~two β chains~~.

Hemoglobin is an iron Fe chelate tightly binding one Fe where it carries a 2+ charge(ferrous ion). If no oxygen molecule is bound it is called deoxyheemoglobin. Deoxyhemoglobin is a tetramer of <scene name='Sandbox4/Alpha2beta2/3'>alpha and beta strands</scene>. The <scene name='Sandbox4/Overall_structure/2'>Overall Structure</scene> is shown here. Deoxyhemoglobin contanis a <scene name='Sandbox4/Heme_group/3'>Heme group</scene>, as well as an ampipathic surface. The

<scene name='Sandbox4/Polar_helix/1'>polar</scene> chain of HIS is highlighted in blue. The <scene name='Sandbox4/Nonpolar_side/1'>nonpolar</scene> chain of PHE is highlighted in green.

~~This shows the <scene name='Sandbox4/Heme_group/3'>Heme group</scene> of deoxyhaemoglobin.~~

Reference:

~~Reference:~~

1).[[ http://www.medcyclopaedia.com/library/topics/volume_i/d/deoxyhaemoglobin.aspx]]

2) http://www.proteopedia.org/wiki/index.php/Hemoglobin

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@@ Line 2: / Line 2: @@
-Name: Jamal Salah
+Name: Jamal Salah and Vishwa Shah!
-      Vishwa Shah
+LKT:
+It's alpha and beta SUBUNITS (2 of each). Say something about the secondary elements (ie 5 alpha helices and 2 beta strands)
+I see problems with greek letters on the JMol, so best to write out alpha and beta. Why did you highlight His which is not hydrophobic?
 {{STRUCTURE_101m |  PDB=101m  |  SCENE=  }}
@@ Line 10: / Line 13: @@
-== '''Deoxyhaemoglobin''' ==
+== '''Deoxyhemoglobin''' ==
 The major oxygen-binding molecule in man, responsible for binding oxygen in the lung and transporting it to the tissues by means of circulation.
-Haemoglobin (Hb) is an iron Fe chelate tightly binding one Fe ion in its II oxidation state where it carries the charge 2+(ferrous ion). If no oxygen molecule is bound it is called deoxyhaemoglobin.Deoxyhaemoglobin is a tetramer of two α and two β chains.
+Hemoglobin is an iron Fe chelate tightly binding one Fe where it carries a 2+ charge(ferrous ion). If no oxygen molecule is bound it is called deoxyheemoglobin. Deoxyhemoglobin is a tetramer of <scene name='Sandbox4/Alpha2beta2/3'>alpha and beta strands</scene>.  The <scene name='Sandbox4/Overall_structure/2'>Overall Structure</scene> is shown here. Deoxyhemoglobin contanis a <scene name='Sandbox4/Heme_group/3'>Heme group</scene>, as well as an ampipathic surface.  The
+<scene name='Sandbox4/Polar_helix/1'>polar</scene> chain of HIS is highlighted in blue.  The <scene name='Sandbox4/Nonpolar_side/1'>nonpolar</scene> chain of PHE is highlighted in green.
-This shows the <scene name='Sandbox4/Heme_group/3'>Heme group</scene> of deoxyhaemoglobin.
+Reference:
-Reference:
 ).[[ http://www.medcyclopaedia.com/library/topics/volume_i/d/deoxyhaemoglobin.aspx]]
+) http://www.proteopedia.org/wiki/index.php/Hemoglobin