2wal: Difference between revisions
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==Crystal Structure of human GADD45gamma== | |||
<StructureSection load='2wal' size='340' side='right'caption='[[2wal]], [[Resolution|resolution]] 2.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2wal]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WAL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WAL FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wal OCA], [https://pdbe.org/2wal PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wal RCSB], [https://www.ebi.ac.uk/pdbsum/2wal PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wal ProSAT]</span></td></tr> | |||
</table> | |||
=== | == Function == | ||
[https://www.uniprot.org/uniprot/GA45G_HUMAN GA45G_HUMAN] Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK. | |||
== Evolutionary Conservation == | |||
== | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wa/2wal_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wal ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Bhattacharya | [[Category: Large Structures]] | ||
[[Category: Buessow | [[Category: Bhattacharya S]] | ||
[[Category: Goetz | [[Category: Buessow K]] | ||
[[Category: Heinemann | [[Category: Goetz F]] | ||
[[Category: Mueller | [[Category: Heinemann U]] | ||
[[Category: Quedenau | [[Category: Mueller JJ]] | ||
[[Category: Roske | [[Category: Quedenau C]] | ||
[[Category: Turnbull | [[Category: Roske Y]] | ||
[[Category: Turnbull AP]] | |||
Latest revision as of 10:10, 9 May 2024
Crystal Structure of human GADD45gamma
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