3bwo: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
 
(7 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{Seed}}
[[Image:3bwo.jpg|left|200px]]


<!--
==L-tryptophan aminotransferase==
The line below this paragraph, containing "STRUCTURE_3bwo", creates the "Structure Box" on the page.
<StructureSection load='3bwo' size='340' side='right'caption='[[3bwo]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3bwo]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BWO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BWO FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
{{STRUCTURE_3bwo| PDB=3bwo |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bwo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bwo OCA], [https://pdbe.org/3bwo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bwo RCSB], [https://www.ebi.ac.uk/pdbsum/3bwo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bwo ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TAA1_ARATH TAA1_ARATH] L-tryptophan aminotransferase involved in auxin (IAA) biosynthesis. Can convert L-tryptophan and pyruvate to indole-3-pyruvic acid (IPA) and alanine. Catalyzes the first step in IPA branch of the auxin biosynthetic pathway. Required for auxin production to initiate multiple change in growth in response to environmental and developmental cues. It is also active with phenylalanine, tyrosine, leucine, alanine, methionine and glutamine. Both TAA1 and TAR2 are required for maintaining proper auxin levels in roots, while TAA1, TAR1 and TAR2 are required for proper embryo patterning. Involved in the maintenance of the root stem cell niches and required for shade avoidance.<ref>PMID:18394996</ref> <ref>PMID:18394997</ref> <ref>PMID:19625638</ref> <ref>PMID:22025724</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bw/3bwo_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3bwo ConSurf].
<div style="clear:both"></div>


===L-tryptophan aminotransferase===
==See Also==
 
*[[Aminotransferase 3D structures|Aminotransferase 3D structures]]
 
== References ==
==About this Structure==
<references/>
3BWO is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BWO OCA].
__TOC__
</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
[[Category: Bowman, M.]]
[[Category: Large Structures]]
[[Category: Chory, J.]]
[[Category: Bowman M]]
[[Category: Ferrer, J L.]]
[[Category: Chory J]]
[[Category: Noel, J P.]]
[[Category: Ferrer J-L]]
[[Category: Pojer, F.]]
[[Category: Noel JP]]
[[Category: Tao, Y.]]
[[Category: Pojer F]]
[[Category: Aminotransferase]]
[[Category: Tao Y]]
[[Category: Auxin synthesis]]
[[Category: Indole-3-pyruvate]]
[[Category: Pyridoxal-5'-phosphate]]
[[Category: Tryptophan]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar  4 14:40:03 2009''