3ixx: Difference between revisions

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'''Unreleased structure'''


The entry 3ixx is ON HOLD until Paper Publication
==The pseudo-atomic structure of West Nile immature virus in complex with Fab fragments of the anti-fusion loop antibody E53==
<SX load='3ixx' size='340' side='right' viewer='molstar' caption='[[3ixx]], [[Resolution|resolution]] 15.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3ixx]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/West_Nile_virus West Nile virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IXX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IXX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 15&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ixx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ixx OCA], [https://pdbe.org/3ixx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ixx RCSB], [https://www.ebi.ac.uk/pdbsum/3ixx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ixx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A7TZT4_WNV A7TZT4_WNV] Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[ARBA:ARBA00003504] Serine protease subunit NS2B: Required cofactor for the serine protease function of NS3.[PROSITE-ProRule:PRU00859]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ix/3ixx_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ixx ConSurf].
<div style="clear:both"></div>


Authors: Cherrier, M.V., Kaufmann, B., Nybakken, G.E., Lok, S.M., Warren, J.T., Nelson, C.A., Kostyuchenko, V.A., Holdaway, H.A., Chipman, P.R., Kuhn, R.J., Diamond, M.S., Rossmann, M.G., Fremont, D.H.
==See Also==
 
*[[Antibody 3D structures|Antibody 3D structures]]
Description: The pseudo-atomic structure of West Nile immature virus in complex with Fab fragments of the anti-fusion loop antibody E53
*[[3D structures of non-human antibody|3D structures of non-human antibody]]
 
__TOC__
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 22 10:25:35 2009''
</SX>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: West Nile virus]]
[[Category: Cherrier MV]]
[[Category: Chipman PR]]
[[Category: Diamond MS]]
[[Category: Fremont DH]]
[[Category: Holdaway HA]]
[[Category: Kaufmann B]]
[[Category: Kostyuchenko VA]]
[[Category: Kuhn RJ]]
[[Category: Lok SM]]
[[Category: Nelson CA]]
[[Category: Nybakken GE]]
[[Category: Rossmann MG]]
[[Category: Warren JT]]
Retrieved from "https://proteopedia.org/3ixx"