3glk: Difference between revisions
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< | ==The biotin carboxylase (BC) domain of human Acetyl-CoA Carboxylase 2 (ACC2)== | ||
<StructureSection load='3glk' size='340' side='right'caption='[[3glk]], [[Resolution|resolution]] 2.10Å' scene=''> | |||
== Structural highlights == | |||
or the | <table><tr><td colspan='2'>[[3glk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GLK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GLK FirstGlance]. <br> | ||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3glk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3glk OCA], [https://pdbe.org/3glk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3glk RCSB], [https://www.ebi.ac.uk/pdbsum/3glk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3glk ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ACACB_HUMAN ACACB_HUMAN] ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gl/3glk_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3glk ConSurf]. | |||
<div style="clear:both"></div> | |||
=== | ==See Also== | ||
*[[Acetyl-CoA carboxylase 3D structures|Acetyl-CoA carboxylase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Kulathila R]] | ||
[[Category: | [[Category: Price A]] | ||
Latest revision as of 09:55, 21 February 2024
The biotin carboxylase (BC) domain of human Acetyl-CoA Carboxylase 2 (ACC2)
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