2p1j: Difference between revisions

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New page: left|200px<br /><applet load="2p1j" size="450" color="white" frame="true" align="right" spinBox="true" caption="2p1j, resolution 2.500Å" /> '''Crystal structure o...
 
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[[Image:2p1j.gif|left|200px]]<br /><applet load="2p1j" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2p1j, resolution 2.500&Aring;" />
'''Crystal structure of a polC-type DNA polymerase III exonuclease domain from Thermotoga maritima'''<br />


==About this Structure==
==Crystal structure of a polC-type DNA polymerase III exonuclease domain from Thermotoga maritima==
2P1J is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Active as [http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2P1J OCA].  
<StructureSection load='2p1j' size='340' side='right'caption='[[2p1j]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
[[Category: DNA-directed DNA polymerase]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[2p1j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P1J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P1J FirstGlance]. <br>
[[Category: Thermotoga maritima]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
[[Category: Almo, S.C.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p1j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p1j OCA], [https://pdbe.org/2p1j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p1j RCSB], [https://www.ebi.ac.uk/pdbsum/2p1j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p1j ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2p1j TOPSAN]</span></td></tr>
[[Category: Bain, K.T.]]
</table>
[[Category: Bonanno, J.B.]]
== Function ==
[[Category: Burley, S.K.]]
[https://www.uniprot.org/uniprot/DPO3_THEMA DPO3_THEMA] Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
[[Category: Izuka, M.]]
== Evolutionary Conservation ==
[[Category: NYSGXRC, New.York.Structural.GenomiX.Research.Consortium.]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Rutter, M.]]
Check<jmol>
[[Category: Sauder, M.J.]]
  <jmolCheckbox>
[[Category: Smith, D.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p1/2p1j_consurf.spt"</scriptWhenChecked>
[[Category: Sridhar, V.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Wasserman, S.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: exonuclease]]
  </jmolCheckbox>
[[Category: new york structural genomix research consortium]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p1j ConSurf].
[[Category: nysgxrc]]
<div style="clear:both"></div>
[[Category: protein structure initiative]]
[[Category: psi-2]]
[[Category: structural genomics]]


''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 13:22:43 2007''
==See Also==
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermotoga maritima MSB8]]
[[Category: Almo SC]]
[[Category: Bain KT]]
[[Category: Bonanno JB]]
[[Category: Burley SK]]
[[Category: Izuka M]]
[[Category: Rutter M]]
[[Category: Sauder JM]]
[[Category: Smith D]]
[[Category: Sridhar V]]
[[Category: Wasserman S]]
Retrieved from "https://proteopedia.org/2p1j"